Single-Cell Transcriptomics Identifies the Adaptation of Scart1+ Vγ6+ T Cells to Skin Residency as Activated Effector Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.05.064
Abstract: IL-17-producing γδ T cells express oligoclonal Vγ4+ and Vγ6+ TCRs, mainly develop in the prenatal thymus, and later persist as long-lived self-renewing cells in all kinds of tissues. However, their exchange between tissues and the mechanisms… read more here.
Keywords: single cell; scart1 cells; cells skin; effector cells ... See more keywords
Role of non‐classical T cells in skin immunity
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Immunology"
DOI: 10.1016/j.molimm.2018.09.024
Abstract: HIGHLIGHTSThe non‐classical MHC pathways are important in skin immunity.CD1 proteins are involved in skin inflammatory diseases.&ggr;&dgr; T cells are key players in skin immunity and tissue homeostasis.Other non‐classical MHC restricted T cells may contribute to… read more here.
Keywords: classical cells; skin immunity; cells skin; non classical ... See more keywords
Plasticity of Epithelial Cells during Skin Wound Healing.
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DOI: 10.1101/cshperspect.a041232
Abstract: Epithelial tissues line the outer surfaces of the mammalian body and protect from external harm. In skin, the epithelium is maintained by distinct stem cell populations residing in the interfollicular epidermis and various niches of… read more here.
Keywords: wound healing; skin wound; cells skin; epithelial cells ... See more keywords
Skin and heart allograft rejection solely by long-lived alloreactive TRM cells in skin of severe combined immunodeficient mice
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abk0270
Abstract: Whether induced tissue-resident memory T (TRM) cells in nonlymphoid organs alone can mediate allograft rejection is unknown. By grafting alloskin or heart into severe combined immunodeficient or Rag2KO mice in which a piece of induced… read more here.
Keywords: trm; allograft rejection; heart; cells skin ... See more keywords
Role of NK Cells in Skin Wound Healing of Mice.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of immunology"
DOI: 10.4049/jimmunol.2200637
Abstract: NK cells are best known for their killing of virus-infected cells and tumor cells via release of cytotoxic factors. However, NK cells can also produce growth factors and cytokines, and thus have the potential to… read more here.
Keywords: healing mice; wound healing; skin wound; cells skin ... See more keywords