Chemosensitization of hepatocellular carcinoma cells to sorafenib by β-caryophyllene oxide-induced inhibition of ABC export pumps
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DOI: 10.1007/s00204-019-02395-9
Abstract: Several ATP-binding cassette (ABC) proteins reduce intracellular concentrations of antitumor drugs and hence weaken the response of cancer cells to chemotherapy. Accordingly, the inhibition of these export pumps constitutes a promising strategy to chemosensitize highly… read more here.
Keywords: hepatocellular carcinoma; cells sorafenib; export pumps; caryophyllene oxide ... See more keywords