Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone
Sign Up to like & getrecommendations! Published in 2017 at "Cell Reports"
DOI: 10.1016/j.celrep.2017.10.111
Abstract: Summary The spleen plays an important role in protective immunity to bloodborne pathogens. Macrophages and dendritic cells (DCs) in the spleen marginal zone capture microbial antigens to trigger adaptive immune responses. Marginal zone macrophages (MZMs)… read more here.
Keywords: marginal zone; zone; spleen marginal; cd8 cells ... See more keywords
mRNA-Loaded Lipid Nanoparticles Targeting Immune Cells in the Spleen for Use as Cancer Vaccines
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15081017
Abstract: mRNA delivery has recently gained substantial interest for possible use in vaccines. Recently approved mRNA vaccines are administered intramuscularly where they transfect antigen-presenting cells (APCs) near the site of administration, resulting in an immune response.… read more here.
Keywords: cells spleen; targeting immune; mrna loaded; immune cells ... See more keywords