Coccomyxa sp.KJ extract affects the fate of T cells stimulated by toxic shock syndrome toxin‐1, a superantigen secreted by Staphylococcus aureus
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DOI: 10.1111/1348-0421.12982
Abstract: T cell stimulation by bacterial superantigens induces a cytokine storm. After T cell activation and inflammatory cytokine secretion, regulatory T cells (Treg) are produced to suppress the immune response. Coccomyxa sp.KJ (IPOD FERM BP‐22254), a… read more here.
Keywords: cells stimulated; stimulated toxic; shock syndrome; coccomyxa extract ... See more keywords
Transcriptional Response in a Sepsis Mouse Model Reflects Transcriptional Response in Sepsis Patients
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DOI: 10.3390/ijms23020821
Abstract: Mortality due to sepsis remains unacceptably high, especially for septic shock patients. Murine models have been used to better understand pathophysiology mechanisms. However, the mouse model is still under debate. Herein we investigated the transcriptional… read more here.
Keywords: response; sepsis; cells stimulated; transcriptional response ... See more keywords
Isoastragaloside I inhibits NF-κB activation and inflammatory responses in BV-2 microglial cells stimulated with lipopolysaccharide.
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DOI: 10.3892/ijmm.2017.3114
Abstract: The excessive activation of microglia in many neurodegenerative diseases is detrimental to neuronal survival. Isoastragaloside I (ISO I) is a natural saponin molecule found within the roots of Astragalus membranaceus, a famous traditional Chinese medicine. In the present study,… read more here.
Keywords: medicine; isoastragaloside inhibits; activation; stimulated lipopolysaccharide ... See more keywords