Mast Cells: Therapeutic Targets For COVID-19 And Beyond.
Sign Up to like & getrecommendations! Published in 2021 at "IUBMB life"
DOI: 10.1002/iub.2552
Abstract: Mast cells (MCs) are innate immune cells that widely distribute throughout all tissues and express a variety of cell surface receptors. Upon activation, MCs can rapidly release a diverse array of pre-formed mediators residing within… read more here.
Keywords: targets covid; mast cells; therapeutic targets; cells therapeutic ... See more keywords
Connexins in endothelial cells as a therapeutic target for solid organ transplantation
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Transplantation"
DOI: 10.1111/ajt.17104
Abstract: Connexins are a class of membrane proteins widely distributed throughout the body and have various functions based on their location and levels of expression. More specifically, connexin proteins expressed in endothelial cells (ECs) have unique… read more here.
Keywords: organ transplantation; cells therapeutic; endothelial cells; transplantation ... See more keywords
Senescent cells: A therapeutic target for osteoporosis
Sign Up to like & getrecommendations! Published in 2022 at "Cell Proliferation"
DOI: 10.1111/cpr.13323
Abstract: Osteoporosis (OP) is a prevalent disorder characterized by the loss of bone mass and the deterioration of bone microarchitecture. OP is attributed to various factors, including menopause (primary), ageing (primary) and the adverse effects of… read more here.
Keywords: therapeutic target; osteoporosis; target osteoporosis; senescence ... See more keywords
Circular RNAs in and out of Cells: Therapeutic Usages of Circular RNAs
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DOI: 10.14348/molcells.2023.2170
Abstract: RNAs are versatile molecules that are primarily involved in gene regulation and can thus be widely used to advance the fields of therapeutics and diagnostics. In particular, circular RNAs which are highly stable, have emerged… read more here.
Keywords: usages circular; rnas cells; circular rnas; endogenous circular ... See more keywords
Engineered T cells and their therapeutic applications in autoimmune diseases
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DOI: 10.24272/j.issn.2095-8137.2021.363
Abstract: Chimeric antigen receptor T cells (CAR-T cells) are engineered recombinant T cells, which were initially used to treat hematopoietic malignancies and are now widely used in the treatment of various diseases. Considering their intrinsic targeting… read more here.
Keywords: therapeutic applications; cells therapeutic; car cells; autoimmune diseases ... See more keywords
B Cells as a Therapeutic Target in Paediatric Rheumatic Disease
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DOI: 10.3389/fimmu.2019.00214
Abstract: B cells carry out a central role in the pathogenesis of autoimmune disease. In addition to the production of autoantibodies, B cells can contribute to disease development by presenting autoantigens to autoreactive T cells and… read more here.
Keywords: paediatric rheumatic; rheumatic disease; disease; cells therapeutic ... See more keywords
Mesenchymal Stem Cells: Therapeutic Mechanisms for Stroke
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23052550
Abstract: Due to aging of the world’s population, stroke has become increasingly prevalent, leading to a rise in socioeconomic burden. In the recent past, stroke research and treatment have become key scientific issues that need urgent… read more here.
Keywords: mechanisms stroke; mesenchymal stem; stem; stem cells ... See more keywords