The Principles of Engineering Immune Cells to Treat Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.01.016
Abstract: Chimeric antigen receptor (CAR) T cells have proven that engineered immune cells can serve as a powerful new class of cancer therapeutics. Clinical experience has helped to define the major challenges that must be met to… read more here.
Keywords: principles engineering; engineering immune; cells treat; cancer ... See more keywords
‘Reprogrammed’ stem cells to treat spinal-cord injuries for the first time
Sign Up to like & getrecommendations! Published in 2019 at "Nature"
DOI: 10.1038/d41586-019-00656-2
Abstract: Approval from Japanese regulators means that trials of induced pluripotent stem cells can begin later this year. Approval from Japanese regulators means that trials of induced pluripotent stem cells can begin later this year. read more here.
Keywords: reprogrammed stem; stem cells; treat spinal; cells treat ... See more keywords
Universal CAR T Cells Treat Leukemia.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-nb2017-023
Abstract: Two infants with relapsed, refractory B-cell acute lymphoblastic leukemia went into complete remission after being treated with CD19-targeting CAR T cells derived from an unmatched donor. The study is the first to demonstrate that a… read more here.
Keywords: treat leukemia; cells treat; universal car; car cells ... See more keywords