Mesenchymal stromal cells in treatment of acute‐on‐chronic liver failure
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.29670
Abstract: alternative target of all active TZD compounds, including rosiglitazone and pioglitazone. We also find it interesting that pioglitazone exhibits beneficial effects on NASH fibrogenesis in clinical trials, whereas the most potent PPARc agonist of the… read more here.
Keywords: mpc; mesenchymal stromal; cells treatment; treatment ... See more keywords
Regulatory T cells in the treatment of disease
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Drug Discovery"
DOI: 10.1038/nrd.2018.148
Abstract: Regulatory T (Treg) cells suppress inflammation and regulate immune system activity. In patients with systemic or organ-specific autoimmune diseases or those receiving transplanted organs, Treg cells are compromised. Approaches to strengthen Treg cell function, either… read more here.
Keywords: treg cells; cells treatment; treatment disease; regulatory cells ... See more keywords
Encapsulated Cells for the Treatment of Diabetes: Danger of Acute Hypoglycemia Following Injury?
Sign Up to like & getrecommendations! Published in 2023 at "Cell Transplantation"
DOI: 10.1177/09636897231163233
Abstract: Transplants comprised of encapsulated islets have shown promise in treating insulin-dependent diabetes. A question raised in the scientific and clinical communities is whether the insulin released from an implanted encapsulation device damaged in an accident… read more here.
Keywords: danger acute; cells treatment; encapsulated cells; diabetes danger ... See more keywords
Contextual reprogramming of CAR-T cells for treatment of HER2+ cancers
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-021-03132-6
Abstract: Background Adoptive transfer of chimeric antigen receptor (CAR)-engineered T cells combined with checkpoint inhibition may prevent T cell exhaustion and improve clinical outcomes. However, the approach is limited by cumulative costs and toxicities. Methods To… read more here.
Keywords: cells treatment; contextual reprogramming; reprogramming car; car cells ... See more keywords
Pluripotent Stem Cells for the Treatment of Retinal Degeneration: Current Strategies and Future Directions
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00743
Abstract: Stem cells have been part of the biomedical landscape since the early 1960s. However, the translation of stem cells to effective therapeutics have met significant challenges, especially for retinal diseases. The retina is a delicate… read more here.
Keywords: cells treatment; retinal degeneration; pluripotent stem; stem ... See more keywords
Serious adverse events and coping strategies of CAR-T cells in the treatment of malignant tumors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1079181
Abstract: Chimeric antigen receptor T (CAR-T) cells technology has been successfully used in the treatment of B cell-derived hematological tumors and multiple myeloma. CAR-T cells are also being studied in a variety of solid tumors. Current… read more here.
Keywords: car; cells treatment; serious adverse; car cells ... See more keywords
Mesenchymal stromal cells for the treatment of Alzheimer’s disease: Strategies and limitations
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.1011225
Abstract: Alzheimer’s disease (AD) is a major cause of age-related dementia and is characterized by progressive brain damage that gradually destroys memory and the ability to learn, which ultimately leads to the decline of a patient’s… read more here.
Keywords: mesenchymal stromal; alzheimer disease; cells treatment; treatment alzheimer ... See more keywords
CAR-T Cells in the Treatment of Urologic Neoplasms: Present and Future
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.915171
Abstract: In recent years, with the breakthrough of CAR-T cells in the treatment of hematological tumors, they are increasingly being used to treat solid tumors, including urologic neoplasms. There are many relatively specific targets for urologic… read more here.
Keywords: urologic neoplasms; treatment urologic; car; cells treatment ... See more keywords
Mesenchymal Stem Cells for the Treatment of Liver Disease: Present and Perspectives
Sign Up to like & getrecommendations! Published in 2019 at "Gut and Liver"
DOI: 10.5009/gnl18412
Abstract: Mesenchymal stem cell transplantation is an emerging therapy for treating chronic liver diseases. The potential of this treatment has been evaluated in preclinical and clinical studies. Although the mechanisms of mesenchymal stem cell transplantation are… read more here.
Keywords: cells treatment; liver disease; stem cells; stem ... See more keywords