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   Articles with "cells tumor" as a keyword



Shaping the immune‐suppressive microenvironment on tumor‐associated myeloid cells through tumor‐derived exosomes

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recommendations! Published in 2024 at "International Journal of Cancer"

DOI: 10.1002/ijc.34921

Abstract: Tumor‐associated myeloid cells (TAMCs) play a crucial role in orchestrating the dynamics of the tumor immune microenvironment. This heterogeneous population encompasses myeloid‐derived suppressor cells, tumor‐associated macrophages and dendritic cells, all of which contribute to the… read more here.

Keywords: myeloid cells; cells tumor; microenvironment; tumor associated ... See more keywords
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γδ cells and tumor microenvironment: A helpful or a dangerous liason?

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recommendations! Published in 2018 at "Journal of Leukocyte Biology"

DOI: 10.1002/jlb.5mr0717-275rr

Abstract: γδ T cells are a subset of T lymphocytes that have been implicated in immunosurveillance against infections and tumors. γδ T cells are endowed with antitumor activities, and hence several γδ T cell‐based small‐scale clinical… read more here.

Keywords: microenvironment helpful; helpful dangerous; dangerous liason; cells tumor ... See more keywords

Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature.

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recommendations! Published in 2017 at "Cancer cell"

DOI: 10.1016/j.ccell.2017.03.005

Abstract: Targeting the tumor vasculature with antibody-drug conjugates (ADCs) is a promising anti-cancer strategy that in order to be realized must overcome several obstacles, including identification of suitable targets and optimal warheads. Here, we demonstrate that… read more here.

Keywords: tumor vasculature; cancer; cells tumor; cd276 positive ... See more keywords

Targeting myeloid cells in the tumor sustaining microenvironment.

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recommendations! Published in 2017 at "Cellular immunology"

DOI: 10.1016/j.cellimm.2017.10.013

Abstract: Myeloid cells are the most abundant cells in the tumor microenvironment (TME). The tumor recruits and modulates endogenous myeloid cells to tumor-associated macrophages (TAM), dendritic cells (DC), myeloid-derived suppressor cells (MDSC) and neutrophils (TAN), to… read more here.

Keywords: targeting myeloid; myeloid cells; tumor sustaining; cancer ... See more keywords

Breast Cancer Stem Cells with Tumor- versus Metastasis-Initiating Capacities Are Modulated by TGFBR1 Inhibition

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recommendations! Published in 2019 at "Stem Cell Reports"

DOI: 10.1016/j.stemcr.2019.05.026

Abstract: Summary Cancer stem cells (CSCs) are defined by their ability to regenerate a tumor upon transplantation. However, it is not yet clear whether tumors contain a single CSC population or different subsets of cells with… read more here.

Keywords: cancer stem; breast cancer; stem; cells tumor ... See more keywords
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Phenotypic plasticity of myeloid cells in glioblastoma development, progression, and therapeutics

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recommendations! Published in 2021 at "Oncogene"

DOI: 10.1038/s41388-021-02010-1

Abstract: Glioblastoma (GBM) is the most common and malignant type of intracranial tumors with poor prognosis. Accumulating evidence suggests that phenotypic alterations of infiltrating myeloid cells in the tumor microenvironment are important for GBM progression. Conventional… read more here.

Keywords: myeloid cells; progression; infiltrating myeloid; cells tumor ... See more keywords

Research on the mechanism of TWSG1 in the malignant progression of glioma cells and tumor-associated macrophage infiltration.

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recommendations! Published in 2024 at "Journal of neuropathology and experimental neurology"

DOI: 10.1093/jnen/nlae067

Abstract: Gliomas are malignant tumors of the central nervous system; current treatment methods have low efficacy. Twisted gastrulation BMP signaling modulator 1 (TWSG1) has been shown to play a role in gliomas but it is not… read more here.

Keywords: macrophage; cells tumor; twsg1; glioma cells ... See more keywords
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ATIM-42. SAFETY AND EFFICACY OF AUTOLOGOUS DENDRITIC CELLS/TUMOR CELL ANTIGEN ADJUVANT THERAPY OF GLIOBLASTOMA MULTIFORME: RESULTS OF 59 CASES

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recommendations! Published in 2018 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noy148.037

Abstract: In our translational research, an immunotherapeutic, ADCTA-G, has been developed to emphasize autologous tumor antigens, DC antigen processing/presentation, enhanced tumor immunogenicity and CTL induction. Two clinical trials, Phase I/II [2003-2005Taiwan DOH/MA 0910072504] and phase II… read more here.

Keywords: glioblastoma multiforme; dendritic cells; cells tumor; cell ... See more keywords

MAIT cells and tumor immunity

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recommendations! Published in 2020 at "Science"

DOI: 10.1126/science.367.6477.523-b

Abstract: Cancer Immunology Mucosal-associated invariant T (MAIT) cells are immune cells that recognize host microbial metabolites presented by major histocompatibility complex class I–related protein 1 (MR1). During bacterial infection, activation of MAIT cells leads to the… read more here.

Keywords: mait cells; tumor immunity; mait; cancer ... See more keywords

Schwann Cells in the Tumor Microenvironment: Need More Attention

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recommendations! Published in 2022 at "Journal of Oncology"

DOI: 10.1155/2022/1058667

Abstract: The tumor microenvironment (TME), which is composed of various cell components and signaling molecules, plays an important role in the occurrence and progression of tumors and has become the central issue of current cancer research.… read more here.

Keywords: schwann cells; tumor microenvironment; microenvironment need; cells tumor ... See more keywords

Abstract 4: A novel humanized mouse model for study of T cells and NK cells in the tumor microenvironment

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recommendations! Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-4

Abstract: Humanized mouse models can be useful for in vivo preclinical evaluation of mechanisms underlying cancer immunotherapy. Most such models involve systemic engraftment of immunocompromised mice with human lymphoid and hematopoietic cells, often using normal donor… read more here.

Keywords: inoculation; model; cells tumor; pbmcs ... See more keywords