Presumption of guilt for T cells in type 1 diabetes: lead culprits or partners in crime depending on age of onset?
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DOI: 10.1007/s00125-020-05298-y
Abstract: Available evidence provides arguments both for and against a primary pathogenic role for T cells in human type 1 diabetes. Genetic susceptibility linked to HLA Class II lends strong support. Histopathology documents HLA Class I… read more here.
Keywords: presumption guilt; cells type; age; guilt cells ... See more keywords
Memory T Cells in Type 1 Diabetes: the Devil is in the Detail
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DOI: 10.1007/s11892-017-0889-9
Abstract: Purpose of ReviewTherapies that target beta-cell antigen-specific T cells subsets have not been as successful in patients with type 1 diabetes as in mice. This might be explained by complexities in the repertoire of beta-cell… read more here.
Keywords: cells type; diabetes devil; memory cells; type diabetes ... See more keywords
Efficiency limits of perovskite solar cells with n-type hole extraction layers
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DOI: 10.1063/5.0059221
Abstract: Transition metal oxides (TMOs) like MoOx are increasingly explored as hole transport layers for perovskite based solar cells. Due to their large work function, the hole collection mechanism of such solar cells are fundamentally different… read more here.
Keywords: cells type; solar cells; perovskite solar; type hole ... See more keywords
Plasmacytoid dendritic cells and type I interferon in the immunological response against warts
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DOI: 10.1111/ced.13187
Abstract: Plasmacytoid dendritic cells (pDCs) are the most potent producers of type I interferons (IFNs), and are involved in the pathogenesis of several cutaneous infectious (especially viral), inflammatory/autoimmune and neoplastic entities. Their role in the pathogenesis… read more here.
Keywords: cells type; type interferon; immunological response; dendritic cells ... See more keywords
Invincible β‐cells in type 1 diabetes
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Diabetes Investigation"
DOI: 10.1111/jdi.13362
Abstract: The classical definition of type 1 diabetes, of which the pathogenesis lies in the autoimmune destruction of beta cells that eventually leads to complete loss of insulin secretion capacity, is recently being revisited with the… read more here.
Keywords: type; invincible cells; type diabetes; cells type ... See more keywords
B cell helper T cells and type 1 diabetes
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DOI: 10.1111/sji.12943
Abstract: Type 1 diabetes is an autoimmune disease typically starting in childhood that culminates in the destruction of insulin‐producing beta cells in the pancreas. Although type 1 diabetes is considered to be a primarily T cell–mediated… read more here.
Keywords: type diabetes; cell helper; helper cells; cells type ... See more keywords
Innate lymphoid cells type 3 in cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1033252
Abstract: Cancer is a multifactorial chronic illness caused by a combination of genetic and environmental factors. A tumor is more than just a collection of cancer cells, it also contains infiltrating and resident host cells that… read more here.
Keywords: ilc3s; cells type; innate lymphoid; type cancer ... See more keywords