Ex vivo activated CD4+ T cells from young calves exhibit Th2-biased effector function with distinct metabolic reprogramming compared to adult cows.
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2022.110418
Abstract: As maternal passive immunity wanes at 6-8 weeks, young calves must rely on their own naïve and developing immune system for protection against pathogens. Typically, an infection in the young induces a T cell-mediated response,… read more here.
Keywords: cd4 cells; cells young; adult cows; young calves ... See more keywords
Lysosomes keep neuronal stem cells young
Sign Up to like & getrecommendations! Published in 2018 at "Science"
DOI: 10.1126/science.359.6381.1227-h
Abstract: Aging An important consequence of aging is loss of regenerative capacity in stem cells, particularly those of the nervous system. Leeman et al. isolated quiescent and activated stem cells from mice and compared their transcriptomes.… read more here.
Keywords: cells young; lysosomes keep; neuronal stem; stem ... See more keywords
Multimodal Tracking of Hematopoietic Stem Cells from Young and Old Mice Labeled with Magnetic–Fluorescent Nanoparticles and Their Grafting by Bioluminescence in a Bone Marrow Transplant Model
Sign Up to like & getrecommendations! Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines9070752
Abstract: This study proposes an innovative way to evaluate the homing and tracking of hematopoietic stem cells from young and old mice labeled with SPIONNIRF-Rh conjugated with two types of fluorophores (NIRF and Rhodamine), and their… read more here.
Keywords: old mice; cells young; model; bone marrow ... See more keywords