Deception through Mimicry: A Cellular Antiviral Strategy
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.11.033
Abstract: Viruses use mimicry to hijack cellular machinery, but can human cells use mimicry as an antiviral approach? Batra et al. identify a novel antiviral restriction factor, RBBP6, by characterizing the cellular interactome of Ebola virus. RBBP6… read more here.
Keywords: ebola virus; antiviral strategy; deception mimicry; cellular antiviral ... See more keywords
ATF3 negatively regulates cellular antiviral signaling and autophagy in the absence of type I interferons
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-08584-9
Abstract: Stringent regulation of antiviral signaling and cellular autophagy is critical for the host response to virus infection. However, little is known how these cellular processes are regulated in the absence of type I interferon signaling.… read more here.
Keywords: cellular antiviral; antiviral signaling; regulates cellular; absence type ... See more keywords
Elucidation of TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010743
Abstract: The tripartite motif (TRIM) family of E3 ubiquitin ligases is well known for its roles in antiviral restriction and innate immunity regulation, in addition to many other cellular pathways. In particular, TRIM25-mediated ubiquitination affects both… read more here.
Keywords: elucidation trim25; ubiquitination targets; trim25 ubiquitination; targets involved ... See more keywords