Cellular cholesterol is required for porcine nidovirus infection
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Virology"
DOI: 10.1007/s00705-017-3545-4
Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine epidemic diarrhea virus (PEDV) are porcine nidoviruses that are considered emerging and re-emerging viral pathogens of pigs that pose a significant economic threat to the global… read more here.
Keywords: nidovirus infection; porcine nidovirus; cholesterol; cellular cholesterol ... See more keywords
A cellular cholesterol sensor
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DOI: 10.1126/science.371.6533.1004-m
Abstract: Structural Biology Cholesterol levels in cells are controlled by the sterol regulatory element–binding protein (SREBP) pathway. When the cell has sufficient cholesterol, the transcription factor that regulates cholesterol metabolism is sequestered at the endoplasmic reticulum… read more here.
Keywords: science; cellular cholesterol; biology; cholesterol ... See more keywords
Retinoic Acid Increases Cellular Cholesterol in Leishmania donovani-Infected Macrophages in an mTOR-Independent Manner
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DOI: 10.1128/spectrum.02699-22
Abstract: People who reside in regions where leishmaniasis is endemic and who lack proteins, iron, zinc, and vitamin A in their diet are more prone to develop visceral leishmaniasis (VL) as a full-blown disease. Vitamin A… read more here.
Keywords: donovani infected; leishmania donovani; cholesterol; mtor ... See more keywords
Cellular cholesterol homeostasis and Alzheimer’s disease
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DOI: 10.1194/jlr.r075630
Abstract: Alzheimer’s disease (AD) is the most common form of dementia in older adults. Currently, there is no cure for AD. The hallmark of AD is the accumulation of extracellular amyloid plaques composed of amyloid-β (Aβ)… read more here.
Keywords: alzheimer disease; cholesterol homeostasis; cholesterol; cellular cholesterol ... See more keywords
Capacity of HDL to Efflux Cellular Cholesterol from Lipid-Loaded Macrophages Is Reduced in Patients with Familial Hypercholesterolemia
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DOI: 10.3390/metabo13020197
Abstract: This study aimed to evaluate the high-density lipoprotein (HDL) capacity to efflux cellular cholesterol from lipid-loaded macrophages to find a reliable and low-cost biomarker with the purpose of better evaluating the risk of premature cardiovascular… read more here.
Keywords: efflux cellular; capacity; capacity hdl; cholesterol ... See more keywords