De novo production of human extracellular matrix supports increased throughput and cellular complexity in 3D skin equivalent model.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of tissue engineering and regenerative medicine"
DOI: 10.1002/term.3071
Abstract: Three-dimensional (3D) tissue models of human skin are being developed to better understand disease phenotypes and to screen new drugs for potential therapies. Several factors will increase the value of these in vitro 3D skin… read more here.
Keywords: complexity; throughput; extracellular matrix; tissue ... See more keywords
Asgard archaea illuminate the origin of eukaryotic cellular complexity
Sign Up to like & getrecommendations! Published in 2017 at "Nature"
DOI: 10.1038/nature21031
Abstract: The origin and cellular complexity of eukaryotes represent a major enigma in biology. Current data support scenarios in which an archaeal host cell and an alphaproteobacterial (mitochondrial) endosymbiont merged together, resulting in the first eukaryotic… read more here.
Keywords: complexity; origin; eukaryotic cellular; cellular complexity ... See more keywords
Coatomer in the universe of cellular complexity
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e19-01-0012
Abstract: Eukaryotic cells possess considerable internal complexity, differentiating them from prokaryotes. Eukaryogenesis, an evolutionary transitional period culminating in the last eukaryotic common ancestor (LECA), marked the origin of the eukaryotic endomembrane system. LECA is reconstructed as… read more here.
Keywords: bar; coatomer universe; cellular complexity; coatomer ... See more keywords
Cellular complexity of the peripheral nervous system: Insights from single-cell resolution
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1098612
Abstract: Single-cell RNA sequencing allows the division of cell populations, offers precise transcriptional profiling of individual cells, and fundamentally advances the comprehension of cellular diversity. In the peripheral nervous system (PNS), the application of single-cell RNA… read more here.
Keywords: cell; peripheral nervous; single cell; cellular complexity ... See more keywords