Cellular consequences of arginine methylation
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DOI: 10.1007/s00018-019-03140-2
Abstract: Arginine methylation is a ubiquitous post-translational modification. Three predominant types of arginine-guanidino methylation occur in Eukarya: mono (Rme1/MMA), symmetric (Rme2s/SDMA), and asymmetric (Rme2a/ADMA). Arginine methylation frequently occurs at sites of protein–protein and protein–nucleic acid interactions,… read more here.
Keywords: methylation; consequences arginine; arginine methylation; physiology ... See more keywords
Insights into the cellular consequences of LRRK2-mediated Rab protein phosphorylation
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DOI: 10.1042/bst20201145
Abstract: Point mutations in leucine-rich repeat kinase 2 (LRRK2) which cause Parkinson's disease increase its kinase activity, and a subset of Rab GTPases have been identified as endogenous LRRK2 kinase substrates. Their phosphorylation correlates with a… read more here.
Keywords: consequences lrrk2; cellular consequences; insights cellular; mediated rab ... See more keywords
Biochemical and cellular consequences of the antithrombin p.Met1? mutation identified in a severe thrombophilic family
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DOI: 10.18632/oncotarget.26059
Abstract: Nature is always the best inspiration for basic research. A family with severe thrombosis and antithrombin deficiency, the strongest anticoagulant, carried a new mutation affecting the translation-start codon of SERPINC1, the gene encoding antithrombin. Expression… read more here.
Keywords: initiation; family; consequences antithrombin; cellular consequences ... See more keywords