Modeling Cellular Differentiation and Reprogramming with Gene Regulatory Networks.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9224-9_2
Abstract: Gene expression regulation is a fundamental cellular process that enables robust functioning of cells. How different genes interact among themselves to coordinate and maintain the overall gene expression profile observed in a cell is a… read more here.
Keywords: differentiation reprogramming; cellular differentiation; differentiation; biology ... See more keywords
Transcription factors NFIA and NFIB induce cellular differentiation in high-grade astrocytoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-019-03352-3
Abstract: Introduction Malignant astrocytomas are composed of heterogeneous cell populations. Compared to grade IV glioblastoma, low-grade astrocytomas have more differentiated cells and are associated with a better prognosis. Therefore, inducing cellular differentiation to alter the behaviour… read more here.
Keywords: cellular differentiation; high grade; nfia nfib; expression ... See more keywords
Metabolites, genome organization, and cellular differentiation gene programs.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2018.01.005
Abstract: The nutrient environment and metabolism play a dynamic role in cellular differentiation and research is elucidating the mechanisms that contribute to this process. Metabolites serve as an effective bridge that helps to translate information about… read more here.
Keywords: metabolites genome; cellular differentiation; differentiation; organization ... See more keywords
Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation
Sign Up to like & getrecommendations! Published in 2020 at "Cell Death and Differentiation"
DOI: 10.1038/s41418-020-0556-6
Abstract: The PIDDosome is a multiprotein complex that drives activation of caspase-2, an endopeptidase originally implicated in apoptosis. Yet, unlike other caspases involved in cell death and inflammation, caspase-2 seems to exert additional versatile functions unrelated… read more here.
Keywords: differentiation uncovering; caspase; cellular differentiation; uncovering piddosome ... See more keywords
Transcription factor Znf2 coordinates with the chromatin remodeling SWI/SNF complex to regulate cryptococcal cellular differentiation
Sign Up to like & getrecommendations! Published in 2019 at "Communications Biology"
DOI: 10.1038/s42003-019-0665-2
Abstract: Cellular differentiation is instructed by developmental regulators in coordination with chromatin remodeling complexes. Much information about their coordination comes from studies in the model ascomycetous yeasts. It is not clear, however, what kind of information… read more here.
Keywords: cellular differentiation; chromatin remodeling; differentiation; swi snf ... See more keywords
Phylotranscriptomics points to multiple independent origins of multicellularity and cellular differentiation in the volvocine algae
Sign Up to like & getrecommendations! Published in 2021 at "BMC Biology"
DOI: 10.1186/s12915-021-01087-0
Abstract: Background The volvocine algae, which include the single-celled species Chlamydomonas reinhardtii and the colonial species Volvox carteri , serve as a model in which to study the evolution of multicellularity and cellular differentiation. Studies reconstructing… read more here.
Keywords: multicellularity cellular; volvocine algae; cellular differentiation; volvocine ... See more keywords
Characterizing Cellular Differentiation Potency and Waddington Landscape via Energy Indicator
Sign Up to like & getrecommendations! Published in 2023 at "Research"
DOI: 10.34133/research.0118
Abstract: The precise characterization of cellular differentiation potency remains an open question, which is fundamentally important for deciphering the dynamics mechanism related to cell fate transition. We quantitatively evaluated the differentiation potency of different stem cells… read more here.
Keywords: cellular differentiation; energy; cell; differentiation potency ... See more keywords