ADAR1 entraps sinister cellular dsRNAs, thresholding antiviral responses.
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DOI: 10.1016/j.it.2021.09.013
Abstract: ADAR1 edits adenosines to inosines in cellular double-stranded (ds)RNA, thereby preventing aberrant activation of antiviral dsRNA sensors, as well as interferon (IFN) induction in Aicardi-Goutières syndrome (AGS) encephalopathy. Recently, Nakahama et al., Tang et al.,… read more here.
Keywords: cellular dsrnas; adar1 entraps; dsrnas thresholding; entraps sinister ... See more keywords