Multi-Omics Reveals Impact of Cysteine Feed Concentration and Resulting Redox Imbalance on Cellular Energy Metabolism and Specific Productivity in CHO Cell Bioprocessing.
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology journal"
DOI: 10.1002/biot.201900565
Abstract: Chinese hamster ovary (CHO) cells are currently the primary host cell lines used in biotherapeutic manufacturing of monoclonal antibodies (mAbs) and other biopharmaceuticals. Cellular energy metabolism and endoplasmic reticulum (ER) stress are known to greatly… read more here.
Keywords: multi omics; metabolism; productivity; cell ... See more keywords
Microplastic Fibers Increase Sublethal Effects of AgNP and AgNO3 in Daphnia magna by Changing Cellular Energy Allocation.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.5136
Abstract: The effects of combined exposure to microplastics and contaminants are still not completely understood. To fill this gap, we assessed the effects of polyethylene terephthalate microplastic fibers (MF) (100 mg/L; 360 µm average length) on… read more here.
Keywords: microplastic fibers; daphnia magna; energy; agno3 daphnia ... See more keywords
OSBP-related protein-2 (ORP2): a novel Akt effector that controls cellular energy metabolism
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-018-2850-8
Abstract: ORP2 is a ubiquitously expressed OSBP-related protein previously implicated in endoplasmic reticulum (ER)—lipid droplet (LD) contacts, triacylglycerol (TG) metabolism, cholesterol transport, adrenocortical steroidogenesis, and actin-dependent cell dynamics. Here, we characterize the role of ORP2 in… read more here.
Keywords: akt; metabolism; orp2; related protein ... See more keywords
The role of AMPK in regulation of Na+,K+-ATPase in skeletal muscle: does the gauge always plug the sink?
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Muscle Research and Cell Motility"
DOI: 10.1007/s10974-020-09594-3
Abstract: AMP-activated protein kinase (AMPK) is a cellular energy gauge and a major regulator of cellular energy homeostasis. Once activated, AMPK stimulates nutrient uptake and the ATP-producing catabolic pathways, while it suppresses the ATP-consuming anabolic pathways,… read more here.
Keywords: skeletal muscle; energy; ampk; role ... See more keywords
AMPK: Sensing Glucose as well as Cellular Energy Status.
Sign Up to like & getrecommendations! Published in 2018 at "Cell metabolism"
DOI: 10.1016/j.cmet.2017.10.009
Abstract: Mammalian AMPK is known to be activated by falling cellular energy status, signaled by rising AMP/ATP and ADP/ATP ratios. We review recent information about how this occurs but also discuss new studies suggesting that AMPK… read more here.
Keywords: energy status; ampk; activation; cellular energy ... See more keywords
Comparison of transcriptomic adjustments to availability of sugar, cellular energy, and oxygen in germinating rice embryos.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of plant physiology"
DOI: 10.1016/j.jplph.2021.153471
Abstract: During germination, the availability of sugars, oxygen, or cellular energy fluctuates under dynamic environmental conditions, likely affecting the global RNA profile of rice genes. Most genes that exhibit sugar-regulation in rice embryos under aerobic conditions… read more here.
Keywords: rice; energy; sugar regulation; sugar ... See more keywords
AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular cell"
DOI: 10.1016/j.molcel.2017.05.032
Abstract: AMPK is a highly conserved master regulator of metabolism, which restores energy balance during metabolic stress both at the cellular and physiological levels. The identification of numerous AMPK targets has helped explain how AMPK restores… read more here.
Keywords: mechanisms cellular; energy; ampk mechanisms; balance ... See more keywords
Regulatory Functions of Cellular Energy Sensor SNF1-Related Kinase1 for Leaf Senescence Delay through ETHYLENE- INSENSITIVE3 Repression
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-03506-1
Abstract: Aging of living organisms is governed by intrinsic developmental programs, of which progression is often under the regulation of their cellular energy status. For example, calorie restriction is known to slow down aging of heterotrophic… read more here.
Keywords: senescence delay; ethylene; senescence; snf1 related ... See more keywords
Chytridiomycosis causes catastrophic organism-wide metabolic dysregulation including profound failure of cellular energy pathways
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-26427-z
Abstract: Chytridiomycosis is among several recently emerged fungal diseases of wildlife that have caused decline or extinction of naïve populations. Despite recent advances in understanding pathogenesis, host response to infection remains poorly understood. Here we modelled… read more here.
Keywords: chytridiomycosis; organism wide; dysregulation; failure ... See more keywords
450 Cellular Energy Monitoring for Diagnosis and Management of Therapy for Sleep Disordered Breathing
Sign Up to like & getrecommendations! Published in 2021 at "Sleep"
DOI: 10.1093/sleep/zsab072.449
Abstract: Polysomnogram (PSG) monitoring, including pulse oximetry, is the current diagnostic standard in sleep medicine. However, potentially confounding aspects of PSG testing include: test site other than the subject’s normal bed, distracting sensors and wires, subjective… read more here.
Keywords: therapy; cellular energy; sleep; psg ... See more keywords
Ultraweak photon emission in strawberry fruit during ripening and aging is related to energy level
Sign Up to like & getrecommendations! Published in 2017 at "Open Life Sciences"
DOI: 10.1515/biol-2017-0046
Abstract: Abstract Background Ultra-weak photon emission (UPE), or biophoton emission, is a phenomenon observed in various living organisms, including plants. In this study, we analyzed the UPE from ripening strawberry fruits, to elucidate its source and… read more here.
Keywords: photon emission; energy; fruit; cellular energy ... See more keywords