The Impact of the Cellular Environment and Aging on Modeling Alzheimer's Disease in 3D Cell Culture Models
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202205037
Abstract: Creating a cellular model of Alzheimer's disease (AD) that accurately recapitulates disease pathology has been a longstanding challenge. Recent studies showed that human AD neural cells, integrated into three‐dimensional (3D) hydrogel matrix, display key features… read more here.
Keywords: ecm; disease; alzheimer disease; cellular environment ... See more keywords
Carbon-Fiber Nanoelectrodes for Real-Time Discrimination of Vesicle Cargo in the Native Cellular Environment.
Sign Up to like & getrecommendations! Published in 2020 at "ACS nano"
DOI: 10.1021/acsnano.9b07318
Abstract: Carbon-fiber microelectrodes have proven to be an indispensable tool for monitoring exocytosis events using amperometry. When positioned adjacent to a cell, a traditional microdisc electrode is well suited for quantification of discrete exocytotic release events.… read more here.
Keywords: cellular environment; native cellular; carbon fiber; carbon ... See more keywords
Structural elucidation of HIV-1 G-quadruplexes in a cellular environment and their ligand binding using responsive 19F-labeled nucleoside probes
Sign Up to like & getrecommendations! Published in 2024 at "Chemical Science"
DOI: 10.1039/d4sc01755b
Abstract: Understanding the structure and recognition of highly conserved regulatory segments of the integrated viral DNA genome that forms unique topologies can greatly aid in devising novel therapeutic strategies to counter chronic infections. In this study,… read more here.
Keywords: cellular environment; environment; ligand; structural elucidation ... See more keywords
Cellular Environment Remodels the Genomic Fabrics of Functional Pathways in Astrocytes
Sign Up to like & getrecommendations! Published in 2020 at "Genes"
DOI: 10.3390/genes11050520
Abstract: We profiled the transcriptomes of primary mouse cortical astrocytes cultured alone or co-cultured with immortalized precursor oligodendrocytes (Oli-neu cells). Filters between the cell types prevented formation of hetero-cellular gap junction channels but allowed for free… read more here.
Keywords: functional pathways; cellular environment; environment remodels; neu cells ... See more keywords
Secondary Structure of Influenza A Virus Genomic Segment 8 RNA Folded in a Cellular Environment
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23052452
Abstract: Influenza A virus (IAV) is a member of the single-stranded RNA (ssRNA) family of viruses. The most recent global pandemic caused by the SARS-CoV-2 virus has shown the major threat that RNA viruses can pose… read more here.
Keywords: structure; secondary structure; cellular environment; rna ... See more keywords