Stereoselective Metabolism of Bupropion to Active Metabolites in Cellular Fractions of Human Liver and Intestine
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DOI: 10.1124/dmd.122.000867
Abstract: Striking stereoselective disposition of the antidepressant and smoking cessation aid bupropion (BUP) and its active metabolites observed clinically influence patients’ response to BUP therapy and its clinically important drug-drug interactions (DDI) with CYP2D6 substrates. However,… read more here.
Keywords: metabolism; cellular fractions; active metabolites; stereoselective metabolism ... See more keywords