Virus restriction: Repurposing an essential cellular function to defend against viruses
Sign Up to like & getrecommendations! Published in 2022 at "Current Biology"
DOI: 10.1016/j.cub.2022.03.012
Abstract: Eukaryotes are continually subjected to viral infections and, in response, have evolved a wide range of defence mechanisms. Two recent studies show how a duplicated copy of a cellular protein needed for cell growth and… read more here.
Keywords: virus restriction; function defend; repurposing essential; restriction repurposing ... See more keywords
Wireless control of cellular function by activation of a novel protein responsive to electromagnetic fields
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-27087-9
Abstract: The Kryptopterus bicirrhis (glass catfish) is known to respond to electromagnetic fields (EMF). Here we tested its avoidance behavior in response to static and alternating magnetic fields stimulation. Using expression cloning we identified an electromagnetic… read more here.
Keywords: electromagnetic fields; cellular function; wireless control; control cellular ... See more keywords
Cellular function given parametric variation in the Hodgkin and Huxley model of excitability
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1808552115
Abstract: Significance Macroscopic cellular function is maintained despite extensive variations in underlying elementary constituents, including the size of the cell, and the number, distribution, and kinetics of their proteins. Here, we take advantage of the sound… read more here.
Keywords: function; huxley model; hodgkin huxley; cellular function ... See more keywords
Mitochondria – More than just batteries for cellular function
Sign Up to like & getrecommendations! Published in 2022 at "Acta Physiologica"
DOI: 10.1111/apha.13852
Abstract: Mitochondria are complex small organelles of eukaryotic cells and build the cellular source of energy. Several morphological features of mitochondria such as the double membrane and the circular DNA structure support the thesis that they… read more here.
Keywords: cell; batteries cellular; mitochondria batteries; cellular function ... See more keywords
Biodynamics: A novel quasi-first principles theory on the fundamental mechanisms of cellular function/dysfunction and the pharmacological modulation thereof
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0202376
Abstract: Cellular function depends on heterogeneous dynamic intra-, inter-, and supramolecular structure-function relationships. However, the specific mechanisms by which cellular function is transduced from molecular systems, and by which cellular dysfunction arises from molecular dysfunction are… read more here.
Keywords: function dysfunction; mechanisms cellular; cellular function; function ... See more keywords
Modulation of Cellular Function by the Urokinase Receptor Signalling: A Mechanistic View
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.818616
Abstract: Urokinase-type plasminogen activator receptor (uPAR or CD87) is a glycosyl-phosphatidyl-inositol anchored (GPI) membrane protein. The uPAR primary ligand is the serine protease urokinase (uPA), converting plasminogen into plasmin, a broad spectrum protease, active on most… read more here.
Keywords: view; function urokinase; upa upar; cellular function ... See more keywords
Transcriptome profiling in response to Kanamycin B reveals its wider non-antibiotic cellular function in Escherichia coli
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.937827
Abstract: Aminoglycosides are not only antibiotics but also have wider and diverse non-antibiotic cellular functions. To elucidate the understanding of non-antibiotic cellular functions, here we report transcriptome-profiling analysis of Escherichia coli in the absence or presence… read more here.
Keywords: transcriptome profiling; non antibiotic; escherichia coli; antibiotic cellular ... See more keywords