Intertwined: SAMHD1 cellular functions, restriction, and viral evasion strategies
Sign Up to like & getrecommendations! Published in 2019 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-019-00593-x
Abstract: SAMHD1 was initially described for its ability to efficiently restrict HIV-1 replication in myeloid cells and resting CD4+ T cells. However, a growing body of evidence suggests that SAMHD1-mediated restriction is by far not limited… read more here.
Keywords: samhd1 cellular; intertwined samhd1; cellular functions; samhd1 ... See more keywords
An evolutionary perspective on the interplays between hydrogen sulfide and oxygen in cellular functions.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2021.108920
Abstract: The physiological effects of the endogenously generated hydrogen sulfide (H2S) have been extensively studied in recent years. This review summarized the role of H2S in the origin of life and H2S metabolism in organisms from… read more here.
Keywords: oxygen; h2s oxygen; evolutionary perspective; cellular functions ... See more keywords
Cellular functions regulated by deubiquitinating enzymes in neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2021 at "Ageing Research Reviews"
DOI: 10.1016/j.arr.2021.101367
Abstract: Neurodegenerative diseases are one of the most common diseases in mankind. Although there are reports of several candidates that cause neurodegenerative diseases, the exact mechanism of pathogenesis is poorly understood. The ubiquitin-proteasome system (UPS) is… read more here.
Keywords: functions regulated; disease; neurodegenerative diseases; cellular functions ... See more keywords
Reprogramming cellular functions with engineered membrane proteins.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2017.06.009
Abstract: Taking inspiration from Nature, synthetic biology utilizes and modifies biological components to expand the range of biological functions for engineering new practical devices and therapeutics. While early breakthroughs mainly concerned the design of gene circuits,… read more here.
Keywords: engineering; functions engineered; reprogramming cellular; cellular functions ... See more keywords
Effects of surface patterning and topography on the cellular functions of tissue engineered scaffolds with special reference to 3D bioprinting.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm01499h
Abstract: The extracellular matrix (ECM) of the tissue organ exhibits a topography from the nano to micrometer range, and the design of scaffolds has been inspired by the host environment. Modern bioprinting aims to replicate the… read more here.
Keywords: effects surface; bioprinting; topography; surface patterning ... See more keywords
The role of interactions of long non-coding RNAs and heterogeneous nuclear ribonucleoproteins in regulating cellular functions
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical Journal"
DOI: 10.1042/bcj20170280
Abstract: Long non-coding RNAs (lncRNAs) are emerging as critical regulators of various biological processes and human diseases. The mechanisms of action involve their interactions with proteins, RNA and genomic DNA. Most lncRNAs display strong nuclear localization.… read more here.
Keywords: coding rnas; long non; non coding; cellular functions ... See more keywords
Cellular functions and molecular mechanisms of non-lysine ubiquitination
Sign Up to like & getrecommendations! Published in 2019 at "Open Biology"
DOI: 10.1098/rsob.190147
Abstract: Protein ubiquitination is of great cellular importance through its central role in processes such as degradation, DNA repair, endocytosis and inflammation. Canonical ubiquitination takes place on lysine residues, but in the past 15 years non-lysine… read more here.
Keywords: functions molecular; lysine ubiquitination; cellular functions; molecular mechanisms ... See more keywords
The Regulation of Cellular Functions by the p53 Protein: Cellular Senescence.
Sign Up to like & getrecommendations! Published in 2017 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a026112
Abstract: Transformed cells have properties that allow them to survive and proliferate inappropriately. These characteristics often arise as a result of mutations caused by DNA damage. p53 suppresses transformation by removing the proliferative or survival capacity… read more here.
Keywords: dna damage; senescence; regulation cellular; cellular functions ... See more keywords
Aromatase inhibitor anastrozole modifies cellular functions in gingival fibroblasts and endothelial cells: possible periodontal complications of aromatase inhibitor treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of periodontal research"
DOI: 10.1111/jre.12881
Abstract: BACKGROUND Recent studies have shown that treatment with aromatase inhibitors contributes to an increased prevalence of periodontitis. OBJECTIVE In this study, we assessed effects of the aromatase inhibitor anastrozole on cellular function of human gingival… read more here.
Keywords: aromatase inhibitor; gingival fibroblasts; inhibitor anastrozole; cellular functions ... See more keywords
Stably Expressed Genes Involved in Basic Cellular Functions
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0170813
Abstract: Stably Expressed Genes (SEGs) whose expression varies within a narrow range may be involved in core cellular processes necessary for basic functions. To identify such genes, we re-analyzed existing RNA-Seq gene expression profiles across 11… read more here.
Keywords: genes involved; basic cellular; stably expressed; expression ... See more keywords
Lipid Exchangers: Cellular Functions and Mechanistic Links With Phosphoinositide Metabolism
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00663
Abstract: Lipids are amphiphilic molecules that self-assemble to form biological membranes. Thousands of lipid species coexist in the cell and, once combined, define organelle identity. Due to recent progress in lipidomic analysis, we now know how… read more here.
Keywords: mechanistic links; exchangers cellular; metabolism; functions mechanistic ... See more keywords