Neurodegeneration in ataxia‐telangiectasia: Multiple roles of ATM kinase in cellular homeostasis
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24522
Abstract: Ataxia‐telangiectasia (A‐T) is characterized by neuronal degeneration, cancer, diabetes, immune deficiency, and increased sensitivity to ionizing radiation. A‐T is attributed to the deficiency of the protein kinase coded by the ATM (ataxia‐telangiectasia mutated) gene. ATM… read more here.
Keywords: roles atm; ataxia telangiectasia; cellular homeostasis;
Regulation and Function of Mitochondria-Lysosome Membrane Contact Sites in Cellular Homeostasis.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2019.02.004
Abstract: Mitochondrial and lysosomal function are intricately related and critical for maintaining cellular homeostasis, as highlighted by multiple diseases linked to dysfunction of both organelles. Recent work using high-resolution microscopy demonstrates the dynamic formation of inter-organelle… read more here.
Keywords: mitochondria lysosome; cellular homeostasis; function; contact ... See more keywords
Mitochondrial Cytochrome c Oxidase Defects Alter Cellular Homeostasis of Transition Metals
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.892069
Abstract: The redox activity of cytochrome c oxidase (COX), the terminal oxidase of the mitochondrial respiratory chain (MRC), depends on the incorporation of iron and copper into its catalytic centers. Many mitochondrial proteins have specific roles… read more here.
Keywords: homeostasis transition; copper; cellular homeostasis; oxidase ... See more keywords
Impact of interorganelle coordination between the conventional early secretory pathway and autophagy in cellular homeostasis and stress response
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1069256
Abstract: The conventional early secretory pathway and autophagy are two essential interconnected cellular processes that are crucial for maintaining cellular homeostasis. The conventional secretory pathway is an anabolic cellular process synthesizing and delivering proteins to distinct… read more here.
Keywords: cellular homeostasis; pathway autophagy; conventional early; early secretory ... See more keywords
Overview of cellular homeostasis-associated nuclear envelope lamins and associated input signals
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1173514
Abstract: With the discovery of the role of the nuclear envelope protein lamin in human genetic diseases, further diverse roles of lamins have been elucidated. The roles of lamins have been addressed in cellular homeostasis including… read more here.
Keywords: cellular homeostasis; nuclear envelope; overview cellular; biology ... See more keywords
NLRX1 Regulation Following Acute Mitochondrial Injury
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.02431
Abstract: Several metabolic, cardiovascular, and neurological disorders are characterized by mitochondrial dysfunction followed by dysregulation of cellular energetics. Mitochondria play an important role in ATP production and cell death regulation. NLRX1, a mitochondria-targeted protein, is known… read more here.
Keywords: cellular homeostasis; mitochondrial injury; following acute; acute mitochondrial ... See more keywords
Jia-ga-song-tang protection against alcoholic liver and intestinal damage
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.981706
Abstract: Gut-liver axis and cellular homeostasis play key roles in alcohol liver disease (ALD). Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a stress-sensitive guarantor of cellular homeostasis. We investigated whether the beneficial effects and underlying mechanisms… read more here.
Keywords: song tang; alcoholic liver; jia song; cellular homeostasis ... See more keywords
NOD-Like Receptors: Guards of Cellular Homeostasis Perturbation during Infection
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22136714
Abstract: The innate immune system relies on families of pattern recognition receptors (PRRs) that detect distinct conserved molecular motifs from microbes to initiate antimicrobial responses. Activation of PRRs triggers a series of signaling cascades, leading to… read more here.
Keywords: homeostasis; cellular homeostasis; infection; nod like ... See more keywords
Challenging Cellular Homeostasis: Spatial and Temporal Regulation of miRNAs
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232416152
Abstract: Mature microRNAs (miRNAs) are single-stranded non-coding RNA (ncRNA) molecules that act in post-transcriptional regulation in animals and plants. A mature miRNA is the end product of consecutive, highly regulated processing steps of the primary miRNA… read more here.
Keywords: cell; cellular homeostasis; challenging cellular; physiology ... See more keywords