Editing of Endogenous Genes in Cellular Immunotherapies
Sign Up to like & getrecommendations! Published in 2020 at "Current Hematologic Malignancy Reports"
DOI: 10.1007/s11899-020-00587-0
Abstract: Purpose of Review T cell-based cellular and antibody immunotherapies have dramatically altered the landscape of cancer treatment over the past decade. Over the same time span, gene editing technologies have enabled unprecedented degrees of genetic… read more here.
Keywords: knock; cell; endogenous genes; editing endogenous ... See more keywords
Genome Engineering for Next-Generation Cellular Immunotherapies.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00340
Abstract: Over the past decade, cellular immunotherapies such as CAR-T, TCR-T, and NK cell therapies have achieved tremendous success in cancer treatment. However, various challenges and obstacles remain, including antigen escape, immunosuppression in the tumor microenvironment,… read more here.
Keywords: genome engineering; cellular immunotherapies; engineering next; next generation ... See more keywords
Cellular immunotherapies for cancer
Sign Up to like & getrecommendations! Published in 2017 at "OncoImmunology"
DOI: 10.1080/2162402x.2017.1306619
Abstract: ABSTRACT Lessons learned over decades on the use of gene and cell therapies have found clinical applicability in the field of cancer immunotherapy. On December 16th, 2016 a symposium was held in Pamplona (Spain) to… read more here.
Keywords: cancer; immunotherapies cancer; cellular immunotherapies; immunotherapy ... See more keywords
The promise of adoptive cellular immunotherapies in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Oncoimmunology"
DOI: 10.1080/2162402x.2019.1673129
Abstract: ABSTRACT Hepatocellular Carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. Current systemic therapies result only in modest benefits and new therapeutic options are critically needed. Some patients show promising clinical responses… read more here.
Keywords: hepatocellular carcinoma; immunotherapies hepatocellular; carcinoma; adoptive cellular ... See more keywords
Imaging cellular immunotherapies and immune cell biomarkers: from preclinical studies to patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2022-004902
Abstract: Cellular immunotherapies have emerged as a successful therapeutic approach to fight a wide range of human diseases, including cancer. However, responses are limited to few patients and tumor types. An in-depth understanding of the complexity… read more here.
Keywords: cellular immunotherapies; imaging cellular; immune cell; immunotherapies immune ... See more keywords
Overview of Cellular Immunotherapies within Transfusion Medicine for the Treatment of Malignant Diseases
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22105120
Abstract: Over the years, transfusion medicine has developed into a broad, multidisciplinary field that covers different clinical patient services such as apheresis technology and the development of stem cell transplantation. Recently, the discipline has found a… read more here.
Keywords: medicine; treatment; transfusion medicine; transfusion ... See more keywords