A novel method to estimate cellular internalization of nanoparticles into gram-negative bacteria: Non-lytic removal of outer membrane and cell wall
Sign Up to like & getrecommendations! Published in 2020 at "NanoImpact"
DOI: 10.1016/j.impact.2020.100283
Abstract: Abstract Bacteria efficiently take up small organic molecules and ions. However, the internalization of particulate forms, specifically nanoparticles (NPs) has been understudied and is a newly-emerging area of interest. However, determination of true cellular internalization… read more here.
Keywords: internalization; gram negative; membrane cell; negative bacteria ... See more keywords
Calcium-Differentiated Cellular Internalization of Allosteric Framework Nucleic Acids for Targeted Payload Delivery.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01434
Abstract: Target delivery systems have extensively shown promising applications in cancer therapy, and many of them function smartly by responding to the cancer cell microenvironment. Here, we for the first time report Ca2+-differentiated cellular internalization of… read more here.
Keywords: nucleic acids; differentiated cellular; cellular internalization; framework nucleic ... See more keywords
Unraveling the Pivotal Role of Atropisomerism for Cellular Internalization
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c05844
Abstract: The intrinsic challenge of large molecules to cross the cell membrane and reach intracellular targets is a major obstacle for the development of new medicines. We report how rotation along a single C–C bond, between… read more here.
Keywords: internalization; atropisomerism cellular; pivotal role; role atropisomerism ... See more keywords
Engineering of Neutrophil Membrane Camouflaging Nanoparticles Realizes Targeted Drug Delivery for Amplified Antitumor Therapy
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s288636
Abstract: Purpose Although the neutrophil membrane (NM)-based nanoparticulate delivery system has exhibited rapid advances in tumor targeting stemmed from the inherited instinct, the antitumor effect requires further improvement due to inefficient cellular internalization in the absence… read more here.
Keywords: neutrophil membrane; camouflaging nanoparticles; cellular internalization; tumor ... See more keywords
Cellular Internalization of Beta-Carotene Loaded Polyelectrolyte Multilayer Capsules by Raman Mapping
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25071477
Abstract: Raman mapping is becoming a very useful tool in investigating cells and cellular components, as well as bioactive molecules intracellularly. In this study, we have encapsulated beta-carotene using a layer-by-layer technique, as a way to… read more here.
Keywords: cellular internalization; raman mapping; internalization beta; beta carotene ... See more keywords
Cellular Internalization and Exiting Behavior of Zwitterionic 4-Armed Star-Shaped Polymers
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28114479
Abstract: The zwitterionic phospholipid polymer poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate) (PMB) is amphiphilic copolymer, and it has been reported to directly penetrate cell membranes and have good cytocompatibility. Conventional PMBs are linear-type random copolymers that are polymerized by… read more here.
Keywords: star; star shaped; shaped polymers; internalization exiting ... See more keywords