Microstructured hydrogel scaffolds containing differential density interfaces promote rapid cellular invasion and vascularization.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.04.027
Abstract: INTRODUCTION Insufficient vascularization of currently available clinical biomaterials has limited their application to optimal wound beds. We designed a hydrogel scaffold with a unique internal microstructure of differential collagen densities to induce cellular invasion and… read more here.
Keywords: collagen; vascularization; invasion; differential density ... See more keywords
Chromosomal Instability Induces Cellular Invasion in Epithelial Tissues.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental cell"
DOI: 10.1016/j.devcel.2018.08.021
Abstract: Most sporadic carcinomas with high metastatic activity show an increased rate of changes in chromosome structure and number, known as chromosomal instability (CIN). However, the role of CIN in driving invasiveness remains unclear. Using an… read more here.
Keywords: cin; induces cellular; instability induces; chromosomal instability ... See more keywords
Cellular Invasion Assay for the Real-Time Tracking of Individual Cells in Spheroid or Tumor-like Mimics.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c05201
Abstract: Cellular invasion is the gateway to metastasis, with cells moving from a primary tumor into neighboring regions of healthy tissue. Invasion assays provide a tractable experimental platform to quantitatively assess cellular movement in the presence… read more here.
Keywords: cellular invasion; invasion assay; cellular movement; invasion ... See more keywords
Whole-Genome Sequencing of Invasion-Resistant Cells Identifies Laminin α2 as a Host Factor for Bacterial Invasion
Sign Up to like & getrecommendations! Published in 2017 at "mBio"
DOI: 10.1128/mbio.02128-16
Abstract: ABSTRACT To understand the role of glycosaminoglycans in bacterial cellular invasion, xylosyltransferase-deficient mutants of Chinese hamster ovary (CHO) cells were created using clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR-associated gene 9 (CRISPR-cas9) gene… read more here.
Keywords: invasion; group streptococcus; host; cellular invasion ... See more keywords