Hsp90 and J-protein family chaperones are not directly involved in cellular iron-sulfur protein assembly and iron regulation in yeast.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14612
Abstract: Systematic studies have revealed interactions between components of the Hsp90 chaperone system and Fe/S protein biogenesis or iron regulation. In addition, two chloroplast-localized DnaJ-like proteins, DJA5 and DJA6, function as specific iron donors in plastidial… read more here.
Keywords: iron; yeast; cellular iron; iron regulation ... See more keywords
Molecular regulation of cellular iron balance
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DOI: 10.1002/iub.1628
Abstract: Handling a life‐supporting yet redox‐active metal like iron represents a significant challenge to cells and organisms that must not only tightly balance intra‐ and extracellular iron concentrations but also chaperone it during its journey from… read more here.
Keywords: iron; molecular regulation; iron balance; cellular iron ... See more keywords
The Role of Estrogen Signaling in Cellular Iron Metabolism in Pancreatic β Cells
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DOI: 10.1097/mpa.0000000000001978
Abstract: Abstract Several lines of evidence suggest that estrogen (17-β estradiol; E2) protects against diabetes mellitus and plays important roles in pancreatic β-cell survival and function. Mounting clinical and experimental evidence also suggest that E2 modulates… read more here.
Keywords: pancreatic cells; iron metabolism; metabolism pancreatic; cellular iron ... See more keywords
Targeting Cellular Iron Homeostasis with Ironomycin in Diffuse Large B-cell Lymphoma
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DOI: 10.1158/0008-5472.can-21-0218
Abstract: Iron homeostasis represents a potential therapeutic target for high-risk patients with DLBCL that can be targeted with ironomycin to induce cell death and to sensitize tumor cells to conventional treatments. read more here.
Keywords: cell; targeting cellular; iron; iron homeostasis ... See more keywords