Cellular mechanisms mediating activity‐dependent extracellular space shrinkage in the retina
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24228
Abstract: Volume transmission plays an essential role in CNS function, with neurotransmitters released from synapses diffusing through the extracellular space (ECS) to distant sites. Changes in the ECS volume fraction (α) will influence the diffusion and… read more here.
Keywords: activity dependent; volume; extracellular space; activity ... See more keywords
Cell interactome in sarcopenia during aging.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cachexia, sarcopenia and muscle"
DOI: 10.1002/jcsm.12937
Abstract: BACKGROUND The diversity between the muscle cellular interactome of dependent and independent elderly people is based on the interrelationships established between different cellular mechanisms, and alteration of this balance modulates cellular activity in muscle tissue… read more here.
Keywords: interactome sarcopenia; cellular mechanisms; muscle; capacity ... See more keywords
Molecular and cellular mechanisms of chemoresistance in pancreatic cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in biological regulation"
DOI: 10.1016/j.jbior.2017.11.007
Abstract: Pancreatic Ductal Adenocarcinoma (PDAC) is one of the most chemoresistant cancers, and current therapies targeting cancer-associated molecular pathways have not given satisfactory results, owing in part to rapid upregulation of alternative compensatory pathways. Most of… read more here.
Keywords: molecular cellular; cellular mechanisms; pancreatic cancer; cancer ... See more keywords
Molecular and Cellular Mechanisms of Neuropathic Pain in Aging.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.3c00010
Abstract: Neuropathic pain is a chronic condition that tends to worsen over time, leading to a significant decline in patients' quality of life. The elderly population is disproportionately affected by this burden, as evidenced by the… read more here.
Keywords: pain aging; mechanisms neuropathic; cellular mechanisms; neuropathic pain ... See more keywords
Cellular mechanisms underlying adult tissue plasticity in Drosophila
Sign Up to like & getrecommendations! Published in 2022 at "Fly"
DOI: 10.1080/19336934.2022.2066952
Abstract: ABSTRACT Adult tissues in Metazoa dynamically remodel their structures in response to environmental challenges including sudden injury, pathogen infection, and nutritional fluctuation, while maintaining quiescence under homoeostatic conditions. This characteristic, hereafter referred to as adult… read more here.
Keywords: adult tissue; adult; tissue plasticity; cellular mechanisms ... See more keywords
Elucidating cellular mechanisms of Saccharomyces cerevisiae tolerant to combined lignocellulosic-derived inhibitors using high-throughput phenotyping and multiomics analyses.
Sign Up to like & getrecommendations! Published in 2018 at "FEMS yeast research"
DOI: 10.1093/femsyr/foy106
Abstract: A robust cell factory that can tolerate combined inhibitory lignocellulosic compounds is essential for the cost-effective lignocellulose-based production of second-generation bioethanol and other bulk chemicals. Following high-throughput phenotyping of a yeast genomic overexpression library, we… read more here.
Keywords: saccharomyces cerevisiae; cellular mechanisms; elucidating cellular; throughput phenotyping ... See more keywords
Unraveling the molecular and cellular mechanisms of stretch marks
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.12974
Abstract: Striae distensae, commonly known as stretch marks, are cutaneous lesions that accompany the hormonal upheavals of the major stages of life: puberty and pregnancy. Stretch marks occur in 90% of women, and they appear as… read more here.
Keywords: molecular cellular; cellular mechanisms; unraveling molecular; stretch marks ... See more keywords
HIV-1 Genomes Are Enriched in Memory CD4+ T-Cells with Short Half-Lives
Sign Up to like & getrecommendations! Published in 2021 at "mBio"
DOI: 10.1128/mbio.02447-21
Abstract: The design of future HIV-1 curative therapies requires a more thorough understanding of the distribution of genetically intact HIV-1 within T-cell subsets as well as the cellular mechanisms that maintain this reservoir. These genetically intact… read more here.
Keywords: genetically intact; hiv; memory; half lives ... See more keywords
Cellular mechanisms promoting cachexia and how they are opposed by sirtuins 1.
Sign Up to like & getrecommendations! Published in 2019 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2018-0479
Abstract: Many chronic diseases are associated with unintentional loss of body weight, which is termed "cachexia". Cachexia is a complex multifactorial syndrome associated with the underlying primary disease, and characterized by loss of skeletal muscle with… read more here.
Keywords: opposed sirtuins; cellular mechanisms; cachexia; mechanisms promoting ... See more keywords
Cuspal Shape Alterations by Bmp4 Directing Cell Proliferation and Apoptosis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of dental research"
DOI: 10.1177/00220345231167769
Abstract: The enamel knot (EK), located at the center of cap stage tooth germs, is a transitory cluster of nondividing epithelial cells. The EK acts as a signaling center that provides positional information for tooth morphogenesis… read more here.
Keywords: cell; cellular mechanisms; cell proliferation; proliferation apoptosis ... See more keywords
Therapeutic Potential and Cellular Mechanisms of Panax Notoginseng on Prevention of Aging and Cell Senescence-Associated Diseases
Sign Up to like & getrecommendations! Published in 2017 at "Aging and Disease"
DOI: 10.14336/ad.2017.0724
Abstract: Owing to a dramatic increase in average life expectancy, most countries in the world are rapidly entering an aging society. Therefore, extending health span with pharmacological agents targeting aging-related pathological changes, are now in the… read more here.
Keywords: cellular mechanisms; notoginseng prevention; potential cellular; panax notoginseng ... See more keywords