Nanozyme-Based Regulation of Cellular Metabolism and their Applications.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202301810
Abstract: Metabolism is the sum of the enzyme-dependent chemical reactions, which produces energy in catabolic process and synthesizes biomass in anabolic process, exhibiting high similarity in mammalian cell, microbial cell, and plant cell. Consequently, the loss… read more here.
Keywords: regulation cellular; metabolism; cell; nanozyme based ... See more keywords
Interplay between cellular metabolism and DNA viruses
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28018
Abstract: Viruses as intracellular pathogens take over the host metabolism and reprogram to facilitate optimal virus production. DNA viruses can cause alterations in several metabolic pathways, including aerobic glycolysis also known as the Warburg effect, pentose… read more here.
Keywords: metabolism; metabolism dna; interplay cellular; dna viruses ... See more keywords
Assaying Mitochondrial Respiration as an Indicator of Cellular Metabolism and Fitness.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6960-9_7
Abstract: Mitochondrial respiration is the most important generator of cellular energy under most circumstances. It is a process of energy conversion of substrates into ATP. The Seahorse equipment allows measuring oxygen consumption rate (OCR) in living… read more here.
Keywords: mitochondrial respiration; indicator cellular; cellular metabolism; respiration ... See more keywords
Evaluating the Role of RARβ Signaling on Cellular Metabolism in Melanoma Using the Seahorse XF Analyzer.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9585-1_12
Abstract: Dysregulation of retinoic acid signaling is implicated in several human cancer types, including melanoma where the gene encoding retinoic acid receptor beta (RARβ) is frequently silenced by promoter hypermethylation. In this chapter, we describe some… read more here.
Keywords: rar; role rar; cellular metabolism; rar signaling ... See more keywords
Role of cellular metabolism in regulating type I interferon responses: Implications for tumour immunology and treatment.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.08.037
Abstract: Type I interferons (IFN) are increasingly recognized for their role in regulating anti-tumour immune responses. However, chronic activation of these pathways can result in immunosuppression and has been linked to poor responses to genotoxic and… read more here.
Keywords: role cellular; cellular metabolism; metabolism regulating; role ... See more keywords
Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP Synthase
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.03.023
Abstract: A complex interplay of environmental factors impacts the metabolism of human cells, but neither traditional culture media nor mouse plasma mimic the metabolite composition of human plasma. Here, we developed a culture medium with polar… read more here.
Keywords: uric acid; metabolism; medium; cellular metabolism ... See more keywords
Monitoring the Cellular Metabolism of a Membrane-Permeant Photo-Caged Phosphatidylinositol 3,4,5-Trisphosphate Derivative.
Sign Up to like & getrecommendations! Published in 2021 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2021.105124
Abstract: To deliver charged lipid derivatives to the cell interior, bioactivatable and photo-activatable protecting groups are frequently used. The intracellular metabolism of the protecting groups, as well as the lipid itself, are key factors that determine… read more here.
Keywords: metabolism; cellular metabolism; photo; protecting groups ... See more keywords
Cellular metabolism and colloids: Realistically linking physiology and biological physical chemistry.
Sign Up to like & getrecommendations! Published in 2020 at "Progress in biophysics and molecular biology"
DOI: 10.1016/j.pbiomolbio.2020.06.002
Abstract: Important concepts from colloidal physical chemistry such as coacervation, phase transitions, emergent properties and ionic association, are currently emerging in the lexicon of cellular biology, prompted mostly by recent experimental observations of liquid phase coexistence… read more here.
Keywords: cellular metabolism; metabolism colloids; chemistry; physiology ... See more keywords
Mimicking Cellular Metabolism in Artificial Cells: Universal Molecule Transport across the Membrane through Vesicle Fusion.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c04696
Abstract: Mass transport across cell membranes is a primary process for cellular metabolism. For this purpose, electrostatically mediated membrane fusion is exploited to transport various small molecules including glucose-6-phosphate, isopropyl β-D-thiogalactoside, and macromolecules such as DNA… read more here.
Keywords: transport across; cellular metabolism; fusion; artificial cells ... See more keywords
The impact of cellular metabolism on chromatin dynamics and epigenetics
Sign Up to like & getrecommendations! Published in 2017 at "Nature Cell Biology"
DOI: 10.1038/ncb3629
Abstract: The substrates used to modify nucleic acids and chromatin are affected by nutrient availability and the activity of metabolic pathways. Thus, cellular metabolism constitutes a fundamental component of chromatin status and thereby of genome regulation.… read more here.
Keywords: chromatin; cellular metabolism; biology; impact cellular ... See more keywords
Targeting cellular metabolism to reduce head and neck cancer growth
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41523-4
Abstract: Head and neck squamous cell carcinoma (HNSCC) presents a major public health concern because of delayed diagnosis and poor prognosis. Malignant cells often reprogram their metabolism in order to promote their survival and proliferation. Aberrant… read more here.
Keywords: metabolism; cellular metabolism; targeting cellular; cancer ... See more keywords