Abstract LB-B26: Novel eIF4A inhibitors target both cellular and microenvironment components in pancreatic ductal adenocarcinoma
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DOI: 10.1158/1535-7163.targ-17-lb-b26
Abstract: We are investigating the potential utility of targeting protein translation via inhibiting the translation initiation factor 4A (eIF4A) with a new class of Pateamine A derivatives to treat pancreatic ductal adenocarcinoma (PDAC). PDAC is one… read more here.
Keywords: microenvironment components; cellular microenvironment; pancreatic ductal; ductal adenocarcinoma ... See more keywords