The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.10.111
Abstract: Cytotoxic immunoglobulin G antibodies are an essential component of therapeutic approaches aimed at depleting self-reactive or malignant cells. More recent evidence suggests that the tissue in which the target cell resides influences the underlying molecular… read more here.
Keywords: cytotoxic antibody; molecular cellular; cellular pathways; antibody activity ... See more keywords
MicroRNA and ER stress in cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2020.12.025
Abstract: The development of biological technologies in genomics, proteomics, and bioinformatics has led to the identification and characterization of the complete set of coding genes and their roles in various cellular pathways in cancer. Nevertheless, the… read more here.
Keywords: microrna stress; cellular pathways; stress; noncoding rnas ... See more keywords
Leukocyte Transcriptional Response in Sepsis.
Sign Up to like & getrecommendations! Published in 2018 at "Shock"
DOI: 10.1097/shk.0000000000001258
Abstract: BACKGROUND The complex host response to sepsis is incompletely understood. The aim of this investigation is to use leukocyte RNA sequencing to characterize biological functions, cellular pathways, and key regulatory molecules driving sepsis pathophysiology. METHODS… read more here.
Keywords: sepsis; regulatory molecules; response; cellular pathways ... See more keywords
Genome-scale identification of cellular pathways required for cell surface recognition.
Sign Up to like & getrecommendations! Published in 2018 at "Genome research"
DOI: 10.1101/gr.231183.117
Abstract: Interactions mediated by cell surface receptors initiate important instructive signaling cues but can be difficult to detect in biochemical assays because they are often highly transient and membrane-embedded receptors are difficult to solubilize in their… read more here.
Keywords: genome scale; pathways required; cellular pathways; surface recognition ... See more keywords
The Potentially Therapeutic Role of EPAC in Curbing the Process of Idiopathic Pulmonary Fibrosis via Differential Cellular Pathways
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s296382
Abstract: Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrosis disease caused by genetic susceptibility (causative) and other indirect risk factors such as smoking, micro-aspiration and air pollution. Repeated damage of lung epithelial cells can… read more here.
Keywords: role; fibrosis; epac; pulmonary fibrosis ... See more keywords
Vitamin D suppresses cellular pathways of diabetes complication in liver
Sign Up to like & getrecommendations! Published in 2019 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2019.36054.8584
Abstract: Objective(s): The aim of this study was to investigate the effect of vitamin D on glucose metabolism, as well as the expression of five key genes involved in the development of diabetes complications in liver… read more here.
Keywords: liver tissue; vitamin suppresses; cellular pathways; gene expression ... See more keywords
Mutant Huntingtin Protein Interaction Map Implicates Dysregulation of Multiple Cellular Pathways in Neurodegeneration of Huntington’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Huntington's Disease"
DOI: 10.3233/jhd-220538
Abstract: Background: Huntington’s disease (HD) is a genetic neurodegenerative disease caused by trinucleotide repeat (CAG) expansions in the human HTT gene encoding the huntingtin protein (Htt) with an expanded polyglutamine tract. Objective: HD models from yeast… read more here.
Keywords: huntingtin protein; htt; huntington disease; disease ... See more keywords
Characterization of the interactome profiling of Mycoplasma fermentans DnaK in cancer cells reveals interference with key cellular pathways
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1022704
Abstract: Chaperone proteins are redundant in nature and, to achieve their function, they bind a large repertoire of client proteins. DnaK is a bacterial chaperone protein that recognizes misfolded and aggregated proteins and drives their folding… read more here.
Keywords: cancer; dnak; interactome profiling; cellular pathways ... See more keywords
Genome-Wide Identification of Cellular Pathways and Key Genes That Respond to Sodium Bicarbonate Stress in Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.831973
Abstract: Sodium bicarbonate (NaHCO3) is an important inorganic salt. It is not only widely used in industrial production and daily life, but is also the main stress in alkaline saline soil. NaHCO3 has a strong ability… read more here.
Keywords: stress; nahco3 stress; sodium bicarbonate; genome wide ... See more keywords
BRG1: Promoter or Suppressor of Cancer? The Outcome of BRG1’s Interaction with Specific Cellular Pathways
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032869
Abstract: BRG1 is one of two catalytic subunits of the SWI/SNF ATP-dependent chromatin-remodeling complex. In cancer, it has been hypothesized that BRG1 acts as a tumor suppressor. Further study has shown that, under certain circumstances, BRG1… read more here.
Keywords: brg1 interaction; suppressor; cellular pathways; brg1 ... See more keywords
Human Papillomavirus and Cellular Pathways: Hits and Targets
Sign Up to like & getrecommendations! Published in 2021 at "Pathogens"
DOI: 10.3390/pathogens10030262
Abstract: The Human Papillomavirus (HPV) is the causative agent of different kinds of tumors, including cervical cancers, non-melanoma skin cancers, anogenital cancers, and head and neck cancers. Despite the vaccination campaigns implemented over the last decades,… read more here.
Keywords: hits targets; cellular pathways; papillomavirus cellular; pathways hits ... See more keywords