Dynamic Transcriptional and Epigenetic Changes Drive Cellular Plasticity in the Liver
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.31704
Abstract: Following liver injury, a fraction of hepatocytes adopt features of biliary epithelial cells (BECs) in a process known as biliary reprogramming. The aim of this study was to elucidate the molecular events accompanying this dramatic… read more here.
Keywords: dynamic transcriptional; cellular plasticity; changes drive; epigenetic changes ... See more keywords
The epigenetic basis of cellular plasticity.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2018.01.003
Abstract: Cellular plasticity is now recognized as a fundamental feature of tissue biology. The steady-state differentiation of stem and progenitor cells into mature cells is, in itself, the index form of cellular plasticity in adult organisms.… read more here.
Keywords: basis cellular; cellular plasticity; epigenetic basis; biology ... See more keywords
Cellular Plasticity in Intestinal Homeostasis and Disease.
Sign Up to like & getrecommendations! Published in 2019 at "Cell stem cell"
DOI: 10.1016/j.stem.2018.11.019
Abstract: The intestinal epithelium is one the fastest renewing tissues in mammals and is endowed with extensive adaptability. The more traditional view of a hierarchical organization of the gut has recently given way to a more… read more here.
Keywords: homeostasis disease; plasticity intestinal; cellular plasticity; intestinal homeostasis ... See more keywords
Cellular Plasticity in Response to Suppression of Storage Proteins in the Brassica napus Embryo[OPEN]
Sign Up to like & getrecommendations! Published in 2020 at "Plant Cell"
DOI: 10.1105/tpc.19.00879
Abstract: Suppressing the genes encoding napin and cruciferin leads to an increase in oleosin accumulation and a reorganization of the intracellular architecture in the developing embryo of oilseed rape. The tradeoff between protein and oil storage… read more here.
Keywords: protein; storage; suppression storage; cellular plasticity ... See more keywords
Abstract SY26-01: Mapping cellular plasticity in tumor progression and drug resistance
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-sy26-01
Abstract: Cellular plasticity is emerging as an important driving force underlying cancer progression and drug resistance. In this talk, I will discuss the concept of cancer cell states present in the tumor prior to treatment, as… read more here.
Keywords: cancer; progression drug; resistance; cellular plasticity ... See more keywords
Developmental Plasticity and Cellular Reprogramming in Caenorhabditis elegans
Sign Up to like & getrecommendations! Published in 2019 at "Genetics"
DOI: 10.1534/genetics.119.302333
Abstract: While Caenorhabditis elegans was originally regarded as a model for investigating determinate developmental programs, landmark studies have subsequently shown that the largely invariant pattern of development in the animal does not reflect irreversibility in rigidly… read more here.
Keywords: developmental plasticity; cellular plasticity; caenorhabditis elegans; plasticity ... See more keywords
Dynamics of Cellular Plasticity in Prostate Cancer Progression
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2020.00130
Abstract: Despite the current advances in the treatment for prostate cancer, the patients often develop resistance to the conventional therapeutic interventions. Therapy-induced drug resistance and tumor progression have been associated with cellular plasticity acquired due to… read more here.
Keywords: cellular plasticity; prostate cancer; cancer; progression ... See more keywords
Behind the Wheel of Epithelial Plasticity in KRAS-Driven Cancers
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.01049
Abstract: Cellular plasticity, a feature associated with epithelial-to-mesenchymal transition (EMT), contributes to tumor cell survival, migration, invasion, and therapy resistance. Phenotypic plasticity of the epithelium is a critical feature in multiple phases of human cancer in… read more here.
Keywords: behind wheel; driven cancers; cellular plasticity; kras driven ... See more keywords
RAS, Cellular Plasticity, and Tumor Budding in Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.01255
Abstract: The high morbidity and mortality of colorectal cancer (CRC) remain a worldwide challenge, despite the advances in prevention, diagnosis, and treatment. RAS alterations have a central role in the pathogenesis of CRC universally recognized both… read more here.
Keywords: colorectal cancer; cellular plasticity; crc; tumor budding ... See more keywords
Yiqi Jianpi Huayu Jiedu Decoction Inhibits Metastasis of Colon Adenocarcinoma by Reversing Hsa-miR-374a-3p/Wnt3/β-Catenin-Mediated Epithelial–Mesenchymal Transition and Cellular Plasticity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.904911
Abstract: Colon adenocarcinoma (COAD) accounts for 95% of colon cancer cases, with the 5-year survival rate significantly affected by local or distant metastases. Yiqi Jianpi Huayu Jiedu decoction (YJHJD), based on the theory of “nourish qi,… read more here.
Keywords: cellular plasticity; hsa mir; mir 374a; wnt3 catenin ... See more keywords
Emerging roles of endoplasmic reticulum stress in the cellular plasticity of cancer cells
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1110881
Abstract: Cellular plasticity is a well-known dynamic feature of tumor cells that endows tumors with heterogeneity and therapeutic resistance and alters their invasion–metastasis progression, stemness, and drug sensitivity, thereby posing a major challenge to cancer therapy.… read more here.
Keywords: cell; stress; plasticity; cellular plasticity ... See more keywords