Ehrlichia SLiM ligand mimetic activates Hedgehog signaling to engage a BCL-2 anti-apoptotic cellular program
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DOI: 10.1371/journal.ppat.1010345
Abstract: Ehrlichia chaffeensis (E. chaffeensis) has evolved eukaryotic ligand mimicry to repurposes multiple cellular signaling pathways for immune evasion. In this investigation, we demonstrate that TRP120 has a novel repetitive short liner motif (SLiM) that activates… read more here.
Keywords: chaffeensis; cellular program; anti apoptotic; infection ... See more keywords