Nanotherapeutics interfere with cellular redox homeostasis for highly improved photodynamic therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2019.119500
Abstract: Redox homeostasis inside malignant cells is a defense mechanism against the reactive oxygen species (ROS)-induced therapy means, but little importance has been paid to this innate barrier. The present study intends to make cancer cells… read more here.
Keywords: homeostasis; cellular redox; redox homeostasis; photodynamic therapy ... See more keywords
Perturbation in cellular redox homeostasis: Decisive regulator of T cell mediated immune responses.
Sign Up to like & getrecommendations! Published in 2019 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2018.12.049
Abstract: Cellular redox homeostasis plays a pivotal role in generation and maintenance of physiological responses. Perturbation in cellular redox status causes modulation in redox sensitive signaling pathways determining the cell fate. Depending on the extent of… read more here.
Keywords: mediated immune; cell mediated; immune responses; redox ... See more keywords
Detection of cellular redox reactions and antioxidant activity assays
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2017.08.008
Abstract: Abstract Living organisms are continuously exposed to reactive oxygen species (ROS) during their lifespan. Small amounts of ROS can act as signal transduction molecules. However, excess ROS cause oxidative stress resulting in multiple adverse effects… read more here.
Keywords: antioxidant activity; cellular redox; detection cellular; redox reactions ... See more keywords
Balancing cellular redox metabolism in microbial electrosynthesis and electro fermentation - A chance for metabolic engineering.
Sign Up to like & getrecommendations! Published in 2018 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2017.12.003
Abstract: More and more microbes are discovered that are capable of extracellular electron transfer, a process in which they use external electrodes as electron donors or acceptors for metabolic reactions. This feature can be used to… read more here.
Keywords: engineering; metabolic engineering; microbial electrosynthesis; cellular redox ... See more keywords
IKK-mediated CYLD phosphorylation and cellular redox activity
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Medicine"
DOI: 10.1186/s10020-022-00439-y
Abstract: Oxidative stress is important in the development of obesity-related nephropathy (ORN). A causal relationship between IKK and ORN via CYLD-mediated inhibition of NRF2 has been described. However, contradictory explanations about the functioning of the mechanisms… read more here.
Keywords: redox activity; phosphorylation cellular; cellular redox; ikk mediated ... See more keywords
Antioxidant metal oxide nanozymes: role in cellular redox homeostasis and therapeutics
Sign Up to like & getrecommendations! Published in 2020 at "Pure and Applied Chemistry"
DOI: 10.1515/pac-2020-0802
Abstract: Abstract Nanomaterials with enzyme-like activity, generally referred to as ‘nanozymes’, find myriad potential in various biomedical fields. More importantly, the nanoparticles that can functionally mimic the activity of cellular antioxidant enzymes attract tremendous interest owing… read more here.
Keywords: redox homeostasis; oxide nanozymes; redox; metal oxide ... See more keywords
Roles of Phase Separation for Cellular Redox Maintenance
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.691946
Abstract: The oxidation reaction greatly alters characteristics of various cellular components. In exchange for efficient energy production, mitochondrial aerobic respiration substantially increases the risk of excess oxidation of cellular biomolecules such as lipids, proteins, nucleic acids,… read more here.
Keywords: roles phase; separation cellular; phase separation; redox ... See more keywords
Is Nucleoredoxin a Master Regulator of Cellular Redox Homeostasis? Its Implication in Different Pathologies
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11040670
Abstract: Nucleoredoxin (NXN), an oxidoreductase enzyme, contributes to cellular redox homeostasis by regulating different signaling pathways in a redox-dependent manner. By interacting with seven proteins so far, namely disheveled (DVL), protein phosphatase 2A (PP2A), phosphofructokinase-1 (PFK1),… read more here.
Keywords: implication different; redox; cellular redox; different pathologies ... See more keywords
Role of Hydrogen Sulfide in NRF2- and Sirtuin-Dependent Maintenance of Cellular Redox Balance
Sign Up to like & getrecommendations! Published in 2018 at "Antioxidants"
DOI: 10.3390/antiox7100129
Abstract: Hydrogen sulfide (H2S) has arisen as a critical gasotransmitter signaling molecule modulating cellular biological events related to health and diseases in heart, brain, liver, vascular systems and immune response. Three enzymes mediate the endogenous production… read more here.
Keywords: nrf2 sirtuin; cellular redox; role; hydrogen sulfide ... See more keywords
Micro RNAs in Regulation of Cellular Redox Homeostasis
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22116022
Abstract: In living cells Reactive Oxygen Species (ROS) participate in intra- and inter-cellular signaling and all cells contain specific systems that guard redox homeostasis. These systems contain both enzymes which may produce ROS such as NADPH-dependent… read more here.
Keywords: homeostasis; redox homeostasis; micro rnas; cellular redox ... See more keywords
Cellular Redox Metabolism Is Modulated by the Distinct Localization of Cyclic Nucleotide Phosphodiesterase 5A Isoforms
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158587
Abstract: 3’-5’ cyclic nucleotide phosphodiesterases (PDEs) are a family of evolutionary conserved cAMP and/or cGMP hydrolysing enzymes, components of transduction pathways regulating crucial aspects of cell life. Among them, cGMP-specific PDE5, being a regulator of vascular… read more here.
Keywords: metabolism modulated; localization; redox metabolism; cellular redox ... See more keywords