Glycan Alteration Imparts Cellular Resistance to a Membrane-Lytic Anticancer Peptide.
Sign Up to like & getrecommendations! Published in 2017 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2016.12.009
Abstract: Although resistance toward small-molecule chemotherapeutics has been well studied, the potential of tumor cells to avoid destruction by membrane-lytic compounds remains unexplored. Anticancer peptides (ACPs) are a class of such agents that disrupt tumor cell… read more here.
Keywords: cellular resistance; membrane lytic; resistance; anticancer ... See more keywords
A mitochondria targeted cascade reaction nanosystem for improved therapeutic effect by overcoming cellular resistance.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00956k
Abstract: Mitigating cellular resistance, which could enhance the sensitivity of tumor cells to treatment, is a promising approach for obtaining better therapeutic outcomes. However, the present designs of materials generally disregard this point, or only focus… read more here.
Keywords: cellular resistance; resistance; mitochondria targeted; therapeutic effect ... See more keywords
375 Importance of cellular resistance to elevated temperature as a determinant of the magnitude of adverse effects of heat stress on farm animals
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Animal Science"
DOI: 10.1093/jas/skz122.215
Abstract: Heat stress can compromise most productive functions of mammals and birds raised for agricultural purposes. Many of the deleterious effects of heat stress are a result of physiological adaptations to maintain constant body temperature. These… read more here.
Keywords: cellular resistance; heat; heat stress; temperature ... See more keywords
Cellular resistance mechanisms in cancer and the new approaches to overcome resistance mechanisms chemotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Saudi medical journal"
DOI: 10.15537/smj.2023.44.4.20220600
Abstract: Despite major advancements in cancer healing approaches over the last few decades, chemotherapy remains the most popular malignancy treatment. Chemotherapeutic drugs are classified into many kinds based on their mechanism of action. Multidrug resistance (MDR)… read more here.
Keywords: cellular resistance; cancer; resistance; medicine ... See more keywords
Nanotechnology in Modern Photodynamic Therapy of Cancer: A Review of Cellular Resistance Patterns Affecting the Therapeutic Response
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12070632
Abstract: Photodynamic therapy (PDT) has emerged as a potential therapeutic option for most localized cancers. Its high measure of specificity and minimal risk of side effects compared to other therapies has put PDT on the forefront… read more here.
Keywords: photodynamic therapy; cellular resistance; resistance; cancer ... See more keywords