Precise Identification of Glioblastoma Micro‐Infiltration at Cellular Resolution by Raman Spectroscopy
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202401014
Abstract: Precise identification of glioblastoma (GBM) microinfiltration, which is essential for achieving complete resection, remains an enormous challenge in clinical practice. Here, the study demonstrates that Raman spectroscopy effectively identifies GBM microinfiltration with cellular resolution in… read more here.
Keywords: spectroscopy; raman spectroscopy; precise identification; cellular resolution ... See more keywords
Rapid Cellular-Resolution Skin Imaging with Optical Coherence Tomography Using All-Glass Multifocal Metasurfaces.
Sign Up to like & getrecommendations! Published in 2023 at "ACS nano"
DOI: 10.1021/acsnano.2c09542
Abstract: Cellular-resolution optical coherence tomography (OCT) is a powerful tool offering noninvasive histology-like imaging. However, like other optical microscopy tools, a high numerical aperture (N.A.) lens is required to generate a tight focus, generating a narrow… read more here.
Keywords: coherence tomography; cellular resolution; resolution; optical coherence ... See more keywords
A Bilayer Microfluidics-Based Elastic Encapsulation Method of Liquid Metal Circuits with Cellular Resolution.
Sign Up to like & getrecommendations! Published in 2025 at "ACS nano"
DOI: 10.1021/acsnano.4c18309
Abstract: Mechanical mismatches at the microscale between bioelectronics and cells severely hinder the successful acquisition of high-quality and stable electrophysiological signals. Room-temperature liquid metals (EGaIn), which possess a near-zero Young's modulus, present a promising material for… read more here.
Keywords: circuits cellular; cellular resolution; resolution; elastic encapsulation ... See more keywords
High-speed, cortex-wide volumetric recording of neuroactivity at cellular resolution using light beads microscopy.
Sign Up to like & getrecommendations! Published in 2021 at "Nature methods"
DOI: 10.1038/s41592-021-01239-8
Abstract: Two-photon microscopy has enabled high-resolution imaging of neuroactivity at depth within scattering brain tissue. However, its various realizations have not overcome the tradeoffs between speed and spatiotemporal sampling that would be necessary to enable mesoscale… read more here.
Keywords: resolution; microscopy; volumetric recording; speed ... See more keywords
sUPRa is a dual-color reporter for unbiased quantification of the unfolded protein response with cellular resolution
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-65611-2
Abstract: The unfolded protein response (UPR) maintains proteostasis upon endoplasmic reticulum (ER) stress, and is initiated by a range of physiological and pathological processes. While there have been advances in developing fluorescent reporters for monitoring individual… read more here.
Keywords: response; cellular resolution; unfolded protein; protein response ... See more keywords
Cellular-resolution optogenetics reveals attenuation-by-suppression in visual cortical neurons
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2318837121
Abstract: Significance How neurons transform inputs into outputs is a fundamental building block of brain computation. Here, we measure neurons’ IO functions in the awake and intact brain, where ongoing network activity influences neurons’ responses to… read more here.
Keywords: cellular resolution; reveals attenuation; attenuation suppression; resolution optogenetics ... See more keywords
Toward mapping the human body at a cellular resolution
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e18-04-0260
Abstract: The adult human body is composed of nearly 37 trillion cells, each with potentially unique molecular characteristics. This Perspective describes some of the challenges and opportunities faced in mapping the molecular characteristics of these cells… read more here.
Keywords: human body; mapping human; body cellular; cellular resolution ... See more keywords
xQTLatlas: a comprehensive resource for human cellular-resolution multi-omics genetic regulatory landscape
Sign Up to like & getrecommendations! Published in 2024 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkae837
Abstract: Abstract Understanding how genetic variants influence molecular phenotypes in different cellular contexts is crucial for elucidating the molecular and cellular mechanisms behind complex traits, which in turn has spurred significant advances in research into molecular… read more here.
Keywords: multi omics; cellular resolution; genetic regulatory; cell ... See more keywords
An Automated Confocal Micro-Extensometer Enables in Vivo Quantification of Mechanical Properties with Cellular Resolution[OPEN]
Sign Up to like & getrecommendations! Published in 2017 at "Plant Cell"
DOI: 10.1105/tpc.17.00753
Abstract: A method of measuring the mechanical properties of cells in living plant tissues in the direction of growth while simultaneously gathering confocal images reveals spatial gradients in extensibility. How complex developmental-genetic networks are translated into… read more here.
Keywords: micro extensometer; mechanical properties; cellular resolution; confocal micro ... See more keywords
Cellular resolution multiplexed FLIM tomography with dual-color Bessel beam.
Sign Up to like & getrecommendations! Published in 2017 at "Biomedical optics express"
DOI: 10.1364/boe.8.000570
Abstract: Fourier multiplexed FLIM (FmFLIM) tomography enables multiplexed 3D lifetime imaging of whole embryos. In our previous FmFLIM system, the spatial resolution was limited to 25 μm because of the trade-off between the spatial resolution and… read more here.
Keywords: resolution; dual color; bessel; cellular resolution ... See more keywords
Bicistronic Expression of a High-Performance Calcium Indicator and Opsin for All-Optical Stimulation and Imaging at Cellular Resolution
Sign Up to like & getrecommendations! Published in 2023 at "eNeuro"
DOI: 10.1523/eneuro.0378-22.2023
Abstract: Abstract State-of-the-art all-optical systems promise unprecedented access to neural activity in vivo, using multiphoton optogenetics to allow simultaneous imaging and control of activity in selected neurons at cellular resolution. However, to achieve wide use of… read more here.
Keywords: cellular resolution; optical stimulation; stimulation; stimulation imaging ... See more keywords