Noncanonical PDK4 action alters mitochondrial dynamics to affect the cellular respiratory status
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DOI: 10.1073/pnas.2120157119
Abstract: Significance Sustained energy stress and cellular dysfunction can cause excessive mitochondrial fragmentation, a feature observed in metabolic diseases, cancer, cardiovascular and neurological disorders, as well as in diseases associated with mitochondrial DNA mutations. We now… read more here.
Keywords: mitochondrial dynamics; respiratory status; pdk4; cellular respiratory ... See more keywords