Multidimensional Quantitative Measurement of Cancer Chemoresistance through Differential ZIF-8 Nanoparticle Cellular Retention.
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DOI: 10.1021/acsami.2c17692
Abstract: Chemoresistance of cancer cells is conventionally quantified by half-maximal inhibitory concentration (IC50) or multidrug resistance gene 1 (MDR1) values, but these metrics can only reflect the overall drug resistance level of a cancer cell line.… read more here.
Keywords: cellular retention; multidimensional quantitative; drug; chemoresistance ... See more keywords