High response rates and transition to transplant after novel targeted and cellular therapies in adults with relapsed/refractory acute lymphoblastic leukemia with Philadelphia‐like fusions
Sign Up to like & getrecommendations! Published in 2023 at "American Journal of Hematology"
DOI: 10.1002/ajh.26908
Abstract: Philadelphia (Ph)‐like acute lymphoblastic leukemia (ALL) is associated with a poor response to standard chemotherapy. However, outcomes with novel antibody and cellular therapies in relapsed/refractory (r/r) Ph‐like ALL are largely unknown. We conducted a single‐center… read more here.
Keywords: philadelphia like; novel; cellular therapies; lymphoblastic leukemia ... See more keywords
Cellular therapies and stem cell applications in trauma.
Sign Up to like & getrecommendations! Published in 2018 at "American journal of surgery"
DOI: 10.1016/j.amjsurg.2018.02.003
Abstract: BACKGROUND As the leading cause of mortality in the United States, trauma management have improved drastically over the past few decades with improved resuscitation and hemorrhage control. Stem cells are being used in an attempt… read more here.
Keywords: applications trauma; stem cell; cellular therapies; cell applications ... See more keywords
Proceedings of the signature series symposium "cellular therapies for orthopaedics and musculoskeletal disease proven and unproven therapies-promise, facts and fantasy," international society for cellular therapies, montreal, canada, may 2, 2018.
Sign Up to like & getrecommendations! Published in 2018 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2018.09.001
Abstract: The Signature Series Symposium "Cellular Therapies for Orthopaedics and Musculoskeletal Disease Proven and Unproven Therapies-Promise, Facts and Fantasy" was held as a pre-meeting of the 26th International Society for Cellular Therapy (ISCT) annual congress in… read more here.
Keywords: symposium; series symposium; cellular therapies; signature series ... See more keywords
Real-time quality control and functional assessment of mesenchymal stem cells for cellular therapies
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DOI: 10.1016/j.jcyt.2019.04.038
Abstract: Background & Aim One of the biggest hurdles in manufacturing of cellular therapies using mesenchymal stem cells (MSCs) is the lack of quantitative tools that simultaneously assess quality and potency of MSCs, which display big… read more here.
Keywords: time; quality; real time; assessment ... See more keywords
Emerging trends in COVID-19 treatment: learning from inflammatory conditions associated with cellular therapies
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DOI: 10.1016/j.jcyt.2020.04.100
Abstract: Coronavirus disease 2019 (SARS-CoV2) is an active global health threat for which treatments are desperately being sought. Even though most people infected experience mild to moderate respiratory symptoms and recover with supportive care, certain vulnerable… read more here.
Keywords: treatment; emerging trends; cellular therapies; covid treatment ... See more keywords
Mobilization and collection of cells in the hematologic compartment for cellular therapies: Stem cell collection with G-CSF/plerixafor, collecting lymphocytes/monocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in hematology"
DOI: 10.1053/j.seminhematol.2019.11.003
Abstract: An essential and influential first step in all cellular therapies is collecting donor or patient cells. In hematopoietic progenitor cell transplantation, autologous or allogeneic hematopoietic progenitor cells (HPCs) are collected from either the bone marrow… read more here.
Keywords: mobilization collection; csf plerixafor; lymphocytes monocytes; cellular therapies ... See more keywords
Cellular therapies for the treatment of immune-mediated GI and liver disease.
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DOI: 10.1093/bmb/ldaa035
Abstract: INTRODUCTION Immune-mediated liver and gastrointestinal diseases are chronic conditions that lack curative treatments. Despite advances in the understanding and treatment of these conditions, they frequently remain refractory to treatment and represent a significant unmet need.… read more here.
Keywords: immune; treatment; clinical trials; immune mediated ... See more keywords
Respiratory Viral Infections in Recipients of Cellular Therapies: A Review of Incidence, Outcomes, Treatment, and Prevention
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DOI: 10.1093/ofid/ofad166
Abstract: Abstract Respiratory viral infections (RVIs) are of major clinical importance in immunocompromised patients and represent a substantial cause of morbidity and mortality in patients with hematologic malignancies and those who have undergone hematopoietic cell transplantation.… read more here.
Keywords: infections recipients; therapies review; viral infections; respiratory viral ... See more keywords
Infections associated with the new 'nibs and mabs' and cellular therapies.
Sign Up to like & getrecommendations! Published in 2020 at "Current Opinion in Infectious Diseases"
DOI: 10.1097/qco.0000000000000656
Abstract: PURPOSE OF REVIEW In recent years, we have witnessed a remarkable surge in the clinical development of effective biological and cellular therapies for the treatment of neoplastic and autoimmune disorders. The present review summarizes our… read more here.
Keywords: treatment; infection; cellular therapies; infections associated ... See more keywords
How do I: Evaluate the safety and legitimacy of unproven cellular therapies?
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DOI: 10.1111/trf.16814
Abstract: Unproven cellular therapies are being offered to patients for a variety of conditions and diseases for which other treatments have failed. The use of untested cellular therapies is a worldwide problem. Practitioners (e.g., physicians, scientists,… read more here.
Keywords: safety legitimacy; unproven cellular; cellular therapies; evaluate safety ... See more keywords
Abstract PR002: Highly parallel knock-in targeting for genome engineering of cellular therapies
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DOI: 10.1158/2326-6074.tumimm20-pr002
Abstract: Genetically-engineered immune cell therapies have proven effective to treat some types of cancer, but most tumors still cannot be cured. Forward genetics with CRISPR loss-of-function screens in T cells have identified some mutations to enhance… read more here.
Keywords: knock; therapies abstract; immunology; cellular therapies ... See more keywords