Killers at the crossroads: The use of innate immune cells in adoptive cellular therapy of cancer
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.19-0423
Abstract: Abstract Adoptive cell therapy (ACT) is an approach to cancer treatment that involves the use of antitumor immune cells to target residual disease in patients after completion of chemo/radiotherapy. ACT has several advantages compared with… read more here.
Keywords: therapy; adoptive cellular; cells adoptive; cancer ... See more keywords
Value-Based Care in Hematopoietic Cell Transplantation and Cellular Therapy: Challenges and Opportunities
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DOI: 10.1007/s11899-018-0444-z
Abstract: Purpose of ReviewImproved tolerability and outcomes after hematopoietic cell transplantation (HCT), along with the availability of alternative donors, have expanded its use. With this growth, and the development of additional cellular therapies, we also aim… read more here.
Keywords: based care; value based; therapy; care ... See more keywords
Guidelines for COVID-19 Management in Hematopoietic Cell Transplantation and Cellular Therapy Recipients
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2020.07.027
Abstract: Abstract There are currently limited data on the epidemiology, clinical manifestations and optimal management of Coronavirus Disease 2019 (COVID-19) in hematopoietic cell transplant and cellular therapy patients. Given the experience with other respiratory viruses, we… read more here.
Keywords: transplantation cellular; hematopoietic cell; epidemiology; therapy ... See more keywords
Pharmacological and genetic strategies for targeting adenosine to enhance adoptive T cell therapy of cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2020.07.002
Abstract: Adoptive cellular therapy involves the ex vivo expansion of immune cells, conventionally T cells, before reinfusion back to the patient. Variations in adoptive cellular therapy include transduction of a patient's T cells with either a… read more here.
Keywords: adoptive cellular; adoptive cell; therapy; enhance adoptive ... See more keywords
Cellular therapy injections in today's orthopedic market: A social media analysis.
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DOI: 10.1016/j.jcyt.2017.08.006
Abstract: BACKGROUND The current state of cellular therapy for musculoskeletal conditions is at a crossroads. Marketing efforts are often outpacing clinical evidence and regulatory control. QUESTIONS/PURPOSES This study was an effort to describe the marketing of… read more here.
Keywords: social media; analysis; tone; market ... See more keywords
Mesenchymal stem versus stromal cells: International Society for Cellular Therapy Mesenchymal Stromal Cell committee position statement on nomenclature.
Sign Up to like & getrecommendations! Published in 2019 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2019.08.002
Abstract: The International Society for Cellular Therapy's Mesenchymal Stromal Cell (ISCT MSC) committee offers a position statement to clarify the nomenclature of mesenchymal stromal cells (MSCs). The ISCT MSC committee continues to support the use of… read more here.
Keywords: international society; mesenchymal stromal; committee; therapy mesenchymal ... See more keywords
Accommodating clinical trials and other externally manufactured cellular therapy products: challenges, lessons learned and creative solutions.
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DOI: 10.1016/j.jcyt.2021.04.005
Abstract: BACKGROUND AIMS The Division of Transfusion Medicine and Cellular Therapy at New York-Presbyterian/Columbia University Irving Medical Center (NYPH-CUIMC) comprises the immunohematology laboratory and blood bank (transfusion service), hemotherapy/apheresis and the cellular therapy laboratory (CTL). The… read more here.
Keywords: clinical trials; lessons learned; therapy products; therapy ... See more keywords
Evaluation of an Adoptive Cellular Therapy-Based Vaccine in a Transgenic Mouse Model of α-synucleinopathy
Sign Up to like & getrecommendations! Published in 2022 at "ACS Chemical Neuroscience"
DOI: 10.1021/acschemneuro.2c00539
Abstract: Aggregated α-synuclein, a major constituent of Lewy bodies plays a crucial role in the pathogenesis of α-synucleinopathies (SPs) such as Parkinson’s disease (PD). PD is affected by the innate and adaptive arms of the immune… read more here.
Keywords: evaluation adoptive; therapy based; cellular therapy; model ... See more keywords
Safety and Efficacy of Iltamiocel Cellular Therapy for the Treatment of Fecal Incontinence. Results of a Phase 1/2 Study.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of surgery"
DOI: 10.1097/sla.0000000000005894
Abstract: OBJECTIVE To examine the safety and efficacy of iltamiocel, an investigational cellular therapy of autologous muscle-derived cells, as a treatment for fecal incontinence (FI) in adults. BACKGROUND Limited therapeutic options are available for patients with… read more here.
Keywords: fecal incontinence; safety efficacy; cellular therapy; incontinence ... See more keywords
Recent advances and clinical pharmacology aspects of Chimeric Antigen Receptor (CAR) T‐cellular therapy development
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Science"
DOI: 10.1111/cts.13349
Abstract: Advances in immuno‐oncology have provided a variety of novel therapeutics that harness the innate immune system to identify and destroy neoplastic cells. It is noteworthy that acceptable safety profiles accompany the development of these targeted… read more here.
Keywords: pharmacology; development; chimeric antigen; car ... See more keywords
Role of flow cytometry in evaluation of the cellular therapy products used in haematopoietic stem cell transplantation.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of laboratory hematology"
DOI: 10.1111/ijlh.13849
Abstract: Cellular therapy nowadays includes various products from haematopoietic stem cells (HSC) collected from bone marrow, peripheral blood, and umbilical cord blood to more complex adoptive immune therapy for the treatment of malignant diseases, and gene… read more here.
Keywords: therapy; flow cytometry; cellular therapy; cell ... See more keywords