The AP‐1 pathway; A key regulator of cellular transformation modulated by oncogenic viruses
Sign Up to like & getrecommendations! Published in 2019 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.2088
Abstract: Cancer progression is critically associated with modulation of host cell signaling pathways. Activator protein‐1 (AP‐1) signaling is one such pathway whose deregulation renders the host more susceptible to cancer development. Oncogenic viruses, including hepatitis B… read more here.
Keywords: cellular transformation; oncogenic viruses; regulator cellular; virus ... See more keywords
Kinetics of cellular transformation and competing precipitation mechanisms during sub-eutectoid annealing of U10Mo alloys
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Alloys and Compounds"
DOI: 10.1016/j.jallcom.2017.06.292
Abstract: Abstract Transformation kinetics of metastable body-centered cubic γ-UMo phase in U-10 wt.% Mo alloy during annealing at sub-eutectoid temperatures of 500 °C and 400 °C has been determined as a function of time using detailed microstructural characterization by… read more here.
Keywords: kinetics cellular; microscopy; cellular transformation; sub eutectoid ... See more keywords
GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi’s Sarcoma-Associated Herpesvirus-Induced Cellular Transformation
Sign Up to like & getrecommendations! Published in 2021 at "mBio"
DOI: 10.1128/mbio.03431-21
Abstract: By performing a genome-wide CRISPR-Cas9 screening, we have identified cellular epigenetic regulators that are essential for KSHV-induced cellular transformation. Among them, GRWD1 regulates epigenetic active mark H3K4me3 by interacting with WDR5 and MLL2 and recruiting… read more here.
Keywords: induced cellular; mark; cellular transformation; kshv ... See more keywords
Direct evidence of cellular transformation by prion-like p53 amyloid infection.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.258316
Abstract: Tumor suppressor p53 mutations are associated with more than 50% of cancers. Aggregation and amyloid formation of p53 is also implicated in cancer pathogenesis, but direct evidence for aggregated p53 amyloids acting as an oncogene… read more here.
Keywords: p53; p53 amyloid; cellular transformation; direct evidence ... See more keywords
Role of Mycoplasma Chaperone DnaK in Cellular Transformation
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21041311
Abstract: Studies of the human microbiome have elucidated an array of complex interactions between prokaryotes and their hosts. However, precise bacterial pathogen–cancer relationships remain largely elusive, although several bacteria, particularly those establishing persistent intra-cellular infections, like… read more here.
Keywords: mycoplasma; dnak; cellular transformation; transformation ... See more keywords