The Wnt/β-catenin pathway is deregulated in cemento-ossifying fibromas.
Sign Up to like & getrecommendations! Published in 2018 at "Oral surgery, oral medicine, oral pathology and oral radiology"
DOI: 10.1016/j.oooo.2017.10.004
Abstract: OBJECTIVE The molecular pathogenesis of cemento ossifying fibroma (COF) is unclear. The purpose of this study was to investigate mutations in 50 oncogenes and tumor suppressor genes, including APC and CTNNB1, in which mutations in… read more here.
Keywords: cemento ossifying; catenin pathway; pathway genes; wnt catenin ... See more keywords
Multiple Cemento-Ossifying Fibroma: A Sign of Hyperparathyroidism-Jaw Tumour Syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Case Reports in Dentistry"
DOI: 10.1155/2023/4664619
Abstract: Hyperparathyroidism-jaw tumour (HPT-JT) syndrome is a rare autosomal dominant disease. It is caused by a gene mutation of the tumour suppressor gene CDC73 that encodes for parafibromin. This syndrome predisposes to a triad occurrence of… read more here.
Keywords: ossifying fibroma; multiple cemento; jaw tumour; hyperparathyroidism jaw ... See more keywords