A Phase 1 Clinical Study Evaluating the Effects of Cenobamate on the QT Interval
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DOI: 10.1002/cpdd.1077
Abstract: Cenobamate is an antiseizure medication for uncontrolled focal seizures. This thorough QT study assessed the effects of therapeutic and supratherapeutic cenobamate doses (maximum recommended dose, 400 mg/day) on correct QT interval (QTc) in healthy adults… read more here.
Keywords: 400 day; day; cenobamate days; cenobamate ... See more keywords
Cénobamate, un nouveau médicament anti-épileptique doté d’un double mécanisme d’action unique et complémentaire
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DOI: 10.1016/j.neurol.2020.01.075
Abstract: Introduction Le cenobamate est un nouveau medicament anti-epileptique recemment approuve par la FDA. Or, jusqu’a present, son mecanisme d’action n’a ete decrit que partiellement. Objectifs Nous presentons ici des donnees supplementaires soutenant le double mecanisme… read more here.
Keywords: anti; mecanisme action; cenobamate; action unique ... See more keywords
A retrospective non‐interventional study evaluating the pharmacokinetic interactions between cenobamate and clobazam
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DOI: 10.1111/epi.17515
Abstract: Cenobamate is an antiseizure medication (ASM) approved for the treatment of partial‐onset seizures in adults. As both an inductor and an inhibitor of hepatic enzymes, cenobamate affects the metabolism of other ASMs, among which is… read more here.
Keywords: cenobamate clobazam; non interventional; cenobamate; interventional study ... See more keywords