Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N
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DOI: 10.1126/science.aar2781
Abstract: Recognizing centromere by kinetochore The kinetochore proteins CENP-N and CENP-C recognize the histone H3 variant CENP-A in the centromeric nucleosome. This ensures proper kinetochore assembly and accurate segregation of chromosomes. Chittori et al. describe the… read more here.
Keywords: microscopy; centromeric nucleosome; cenp; cenp cenp ... See more keywords
CENP-C/H/I/K/M/T/W/N/L and hMis12 but not CENP-S/X participate in complex formation in the nucleoplasm of living human interphase cells outside centromeres
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DOI: 10.1371/journal.pone.0192572
Abstract: Kinetochore proteins assemble onto centromeric chromatin and regulate DNA segregation during cell division. The inner kinetochore proteins bind centromeres while most outer kinetochore proteins assemble at centromeres during mitosis, connecting the complex to microtubules. Here,… read more here.
Keywords: living human; cenp; cenp cenp; interphase cells ... See more keywords