Targeted De Novo Centromere Formation in Drosophila Reveals Plasticity and Maintenance Potential of CENP-A Chromatin.
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DOI: 10.1016/j.devcel.2020.01.005
Abstract: Centromeres are essential for accurate chromosome segregation and are marked by centromere protein A (CENP-A) nucleosomes. Mis-targeted CENP-A chromatin has been shown to seed centromeres at non-centromeric DNA. However, the requirements for such de novo… read more here.
Keywords: drosophila; centromere formation; chromatin; novo centromere ... See more keywords