N6-methyladenosine modification of CENPF mRNA facilitates gastric cancer metastasis via regulating FAK nuclear export.
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DOI: 10.1002/cac2.12443
Abstract: BACKGROUND N6-methyladenosine (m6 A) modification is the most common modification that occurs in eukaryotes. Although substantial effort has been made in the prevention and treatment of gastric cancer (GC) in recent years, the prognosis of… read more here.
Keywords: metastasis; modification; cenpf; modification cenpf ... See more keywords
CENPF as an independent prognostic and metastasis biomarker corresponding to CD4+ memory T cells in cutaneous melanoma
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DOI: 10.1111/cas.15303
Abstract: Owing to recent advances in immunotherapies, the overall survival of patients with skin cutaneous melanoma (SKCM) has increased; however, the 5‐year survival rate of metastatic patients remains poor. Skin cutaneous melanoma—upregulated genes were screened via… read more here.
Keywords: metastasis; cd4 memory; cenpf; melanoma ... See more keywords
Overexpression of CENPF correlates with poor prognosis and tumor bone metastasis in breast cancer
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DOI: 10.1186/s12935-019-0986-8
Abstract: BackgroundCentromere Protein F (CENPF) associates with the centromere–kinetochore complex and influences cell proliferation and metastasis in several cancers. The role of CENPF in breast cancer (BC) bone metastasis remains unclear.MethodsUsing the ONCOMINE database, we compared… read more here.
Keywords: metastasis; bone metastasis; cenpf; breast cancer ... See more keywords
Combined multiomics analysis reveals the mechanism of CENPF overexpression-mediated immune dysfunction in diffuse large B-cell lymphoma in vitro
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DOI: 10.3389/fgene.2022.1072689
Abstract: Diffuse large B-cell lymphoma (DLBCL) is one of the most common aggressive B-cell lymphomas with significant heterogeneity. More than half of patients are cured, but 40%–45% still face relapse or develop drug resistance, and the… read more here.
Keywords: cell; cenpf; dlbcl; large cell ... See more keywords
Deciphering the Prognostic and Therapeutic Significance of Cell Cycle Regulator CENPF: A Potential Biomarker of Prognosis and Immune Microenvironment for Patients with Liposarcoma
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DOI: 10.3390/ijms24087010
Abstract: Liposarcoma (LPS) is one of the most common subtypes of sarcoma with a high recurrence rate. CENPF is a regulator of cell cycle, differential expression of which has been shown to be related with various… read more here.
Keywords: prognosis immune; cell cycle; expression; cenpf ... See more keywords
Overexpression of CENPF is associated with progression and poor prognosis of lung adenocarcinoma
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DOI: 10.7150/ijms.49041
Abstract: Background and aim: The molecular signatures of lung adenocarcinoma (LUAD) are not well understood. Centromere protein F (CENPF) has been shown to promote oncogenesis in many cancers; however, its role in LUAD has not been… read more here.
Keywords: lung adenocarcinoma; luad; cenpf; expression ... See more keywords
Centromere Protein F (CENPF) Serves as a Potential Prognostic Biomarker and Target for Human Hepatocellular Carcinoma
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DOI: 10.7150/jca.52187
Abstract: Overexpression of Centromere Protein F (CENPF) is associated with tumorigenesis of many human malignant tumors. But the molecular mechanism and prognostic value of CENPF in patients with hepatocellular carcinoma (HCC) are still unclear. In this… read more here.
Keywords: hepatocellular carcinoma; hcc; cenpf; centromere protein ... See more keywords