Identification of central amygdala and trigeminal motor nucleus connectivity in humans: An ultra‐high field diffusion MRI study
Sign Up to like & getrecommendations! Published in 2022 at "Human Brain Mapping"
DOI: 10.1002/hbm.26104
Abstract: The neuroanatomical circuitry of jaw muscles has been mostly explored in non‐human animals. A recent rodent study revealed a novel circuit from the central amygdala (CeA) to the trigeminal motor nucleus (5M), which controls biting… read more here.
Keywords: connectivity; circuit; central amygdala; trigeminal motor ... See more keywords
Distinct circuits in rat central amygdala for defensive behaviors evoked by socially signaled imminent versus remote danger
Sign Up to like & getrecommendations! Published in 2021 at "Current Biology"
DOI: 10.1016/j.cub.2021.03.047
Abstract: Animals display a rich repertoire of defensive responses adequate to the threat proximity. In social species, these reactions can be additionally influenced by the behavior of fearful conspecifics. However, the majority of neuroscientific studies on… read more here.
Keywords: versus remote; defensive responses; imminent versus; remote ... See more keywords
The paraventricular thalamus input to central amygdala controls depression-related behaviors
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2021.113744
Abstract: The dysregulation of neuronal networks may contribute to the etiology of major depressive disorder (MDD). However, the neural connections underlying the symptoms of MDD have yet to be elucidated. Here, we observed that glutamatergic neurons… read more here.
Keywords: depression; related behaviors; central amygdala; paraventricular thalamus ... See more keywords
Yummy or yucky? Ask your central amygdala
Sign Up to like & getrecommendations! Published in 2017 at "Nature Neuroscience"
DOI: 10.1038/nn.4639
Abstract: Central amygdala directs behavioral responses to emotionally salient stimuli. While most studies have focused on aversive responses, some central amygdala neurons promote feeding and are positively reinforcing. read more here.
Keywords: central amygdala; ask central; yucky ask; amygdala ... See more keywords
A brainstem-central amygdala circuit underlies defensive responses to learned threats
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Psychiatry"
DOI: 10.1038/s41380-019-0599-6
Abstract: Norepinephrine (NE) plays a central role in the acquisition of aversive learning via actions in the lateral nucleus of the amygdala (LA) [ 1 , 2 ]. However, the function of NE in expression of… read more here.
Keywords: brainstem central; defensive responses; amygdala circuit; central amygdala ... See more keywords
Food and water intake are regulated by distinct central amygdala circuits revealed using intersectional genetics
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-58144-3
Abstract: The central amygdala (CeA) plays a crucial role in defensive and appetitive behaviours. It contains genetically defined GABAergic neuron subpopulations distributed over three anatomical subregions, capsular (CeC), lateral (CeL), and medial (CeM). The roles that… read more here.
Keywords: genetics; food; using intersectional; central amygdala ... See more keywords
A central amygdala to zona incerta projection is required for acquisition and remote recall of conditioned fear memory
Sign Up to like & getrecommendations! Published in 2018 at "Nature Neuroscience"
DOI: 10.1038/s41593-018-0248-4
Abstract: The formation and retrieval of conditioned fear memories critically depend on the amygdala. Here we identify an inhibitory projection from somatostatin-positive neurons in the central amygdala to parvalbumin-positive neurons in the zona incerta that is… read more here.
Keywords: central amygdala; fear memory; conditioned fear; projection ... See more keywords
A subpopulation of projections from the parabrachial nucleus to the central amygdala mediates itch
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-08612-z
Abstract: The parabrachial nucleus (PBN) plays a crucial role in transmitting itch and affective pain signals to the brain regions such as the central amygdala (CeA). While CGRP+ PBN neurons have been implicated in itch processing,… read more here.
Keywords: cea; central amygdala; itch; pbn ... See more keywords
Trans-synaptic signaling through GRID1/glutamate receptor delta-1 and CBLN1/cerebellin-1 facilitates autophagic flux in central amygdala and prevents chronic pain.
Sign Up to like & getrecommendations! Published in 2025 at "Autophagy"
DOI: 10.1080/15548627.2025.2574968
Abstract: ABSTRACT Central amygdala (CeA) is a component of the spino-parabrachio-amygdala nociceptive pathway. Neuroplasticity in this pathway, such as increased cellular excitability and excitatory neurotransmission, play a key role in the development and persistence of chronic… read more here.
Keywords: receptor; central amygdala; pain; cbln1 ... See more keywords
Depo-Provera increases neural activity in the central amygdala of reindeer bulls.
Sign Up to like & getrecommendations! Published in 2018 at "Translational animal science"
DOI: 10.1093/tas/txy075
Abstract: Reindeer bulls are difficult to manage and dangerous to handlers during the rutting period. Progesterone agonists have been used anecdotally in the field to favorably influence behavior, but effects on reproductive signaling have not been… read more here.
Keywords: neural activity; activity; depo provera; central amygdala ... See more keywords
GABAergic Neurons in the Central Amygdala Promote Emergence from Isoflurane Anesthesia in Mice
Sign Up to like & getrecommendations! Published in 2024 at "Anesthesiology"
DOI: 10.1097/aln.0000000000005279
Abstract: Background: Recent evidence indicates that general anesthesia and sleep–wake behavior share some overlapping neural substrates. γ-Aminobutyric acid–mediated (GABAergic) neurons in the central amygdala have a high firing rate during wakefulness and play a role in… read more here.
Keywords: central amygdala; gabaergic neurons; isoflurane anesthesia;