Articles with "central composite" as a keyword



Central Composite Design Optimization for the Synthesis of Butyl Acetate Catalyzed by Liquid Lipase.

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Published in 2025 at "Biotechnology and applied biochemistry"

DOI: 10.1002/bab.70050

Abstract: Butyl acetate, a valuable flavor ester, is conventionally synthesized through acid-catalyzed reactions, which suffer from environmental concerns and inefficiencies. This study explores a greener alternative using liquid lipase Novozym 400238 for its enzymatic synthesis. The… read more here.

Keywords: butyl acetate; synthesis; liquid lipase; central composite ... See more keywords

Extraction of diclofenac by SiO2 -NH2 @Fe3 O4 and its determination; Central composite design.

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Published in 2019 at "Journal of separation science"

DOI: 10.1002/jssc.201900887

Abstract: In this work, magnetic nanoparticles (Fe3 O4 ) were prepared by simple co-precipitation method in aqueous medium and then subsequently modified with tetraethyl orthosilicate and 3-aminopropyl triethylenesilane. The properties of particles were characterized by FT-IR,… read more here.

Keywords: extraction; nh2 fe3; sio2 nh2; microscopy ... See more keywords

Valorization of Crataegus azarolus stones for the removal of textile anionic dye by central composite rotatable design using cubic model: optimization, isotherm, and kinetic studies

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Published in 2017 at "Environmental Science and Pollution Research"

DOI: 10.1007/s11356-017-9606-0

Abstract: In this study, the central composite rotatable design (CCRD) was used in the optimization of the operating parameters for the removal of the direct blue 86 (DB86), an anionic dye, because of its hazardous impact… read more here.

Keywords: anionic dye; rotatable design; model; central composite ... See more keywords
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Optimization of Headspace SPME GC × GC-TOF/MS Analysis of Volatile Organic Compounds in Edible Oils by Central Composite Design for Adulteration Detection of Edible Oil

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Published in 2020 at "Food Analytical Methods"

DOI: 10.1007/s12161-020-01741-3

Abstract: Volatile flavor components are critical to edible oils and influence consumption choice. Meanwhile, volatile organic compounds (VOCs) in edible oils are also potential biomarkers to detect adulterated products. However, VOCs are usually complex, unstable, and easily… read more here.

Keywords: organic compounds; edible oils; volatile organic; analysis ... See more keywords

Optimization of melt-spinning parameters of poly(ethylene terephthalate) partially oriented multi-filament yarn in an industrial scale: Central composite design approach

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Published in 2017 at "Fibers and Polymers"

DOI: 10.1007/s12221-017-1119-4

Abstract: In this study, central composite design (CCD) based on response surface methodology (RSM) was employed to optimize parameters of melt-spinning process of poly(ethylene terephthalate) partially oriented multifilament yarn (POMFY). On the basis of a four-variable… read more here.

Keywords: melt spinning; poly ethylene; central composite; ethylene terephthalate ... See more keywords

Production of High Quality Fish Oil by Enzymatic Protein Hydrolysis from Cultured Atlantic Salmon By-Products: Investigation on Effect of Various Extraction Parameters Using Central Composite Rotatable Design

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Published in 2018 at "Waste and Biomass Valorization"

DOI: 10.1007/s12649-017-9998-6

Abstract: Salmon oil was extracted from cultured Atlantic salmon by-product mix (head, frame and viscera) through enzymatic extraction, with experimental combinations of different enzyme (Sea-B-Zyme L200 enzyme) concentrations (0.09–2.91%) and temperature levels (38–52 °C), generated and analyzed… read more here.

Keywords: cultured atlantic; central composite; acid; composite rotatable ... See more keywords

Optimization of Pistacia lentiscus Oil Transesterification Process Using Central Composite Design

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Published in 2018 at "Waste and Biomass Valorization"

DOI: 10.1007/s12649-018-0257-2

Abstract: In the present work, Pistacia lentiscus (PL) biodiesel was produced by converting PL oil with a single-step homogenous alkali catalyzed transesterification process. Several ethanol/vegetable oil molar ratio values (6–12:1), temperatures from 40 to 70 °C and… read more here.

Keywords: process; transesterification process; central composite; pistacia lentiscus ... See more keywords

Development and Optimization of Alendronate Sodium Loaded PLGA Nanoparticles by Central Composite Design

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Published in 2019 at "Macromolecular Research"

DOI: 10.1007/s13233-019-7119-z

Abstract: AbstractAlendronate sodium (AS) which supresses the activity of osteoclastic cells and leads to the inhibition of bone resorption, is one of the most clinically preferred drug for the treatment of osteoporosis. The purpose of this… read more here.

Keywords: plga nanoparticles; nanoparticle; sodium; method ... See more keywords

Application of central composite design for electrochemical oxidation of reactive dye on Ti/MWCNT electrode

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Published in 2019 at "Journal of the Iranian Chemical Society"

DOI: 10.1007/s13738-019-01834-9

Abstract: In the present study, degradation of Reactive Orange 7 dye was investigated using a new designed titanium electrode, in which a plate of Ti was coated with multi-walled carbon nanotubes (Ti/MWCNT) via electrophoretic deposition technique.… read more here.

Keywords: mwcnt; dye; central composite; electrode ... See more keywords

Synthesis of hierarchical nanoporous HY zeolites from activated kaolin, a central composite design optimization study

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Published in 2017 at "Advanced Powder Technology"

DOI: 10.1016/j.apt.2017.03.008

Abstract: In this article, we investigated the optimum formulation towards synthesis of hierarchical nanoporous HY zeolites from acid activate kaolin. A central composite design (CCD) helped to examine the influence of aging (X1), crystallization (X2) and… read more here.

Keywords: hierarchical nanoporous; synthesis hierarchical; nanoporous zeolites; central composite ... See more keywords

Optimization of a single HPLC-PDA method for quantifying Metformin, Gliclazide, Pioglitazone, Dapagliflozin, Empagliflozin, Saxagliptin, Linagliptin and Teneligliptin using central composite design.

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Published in 2019 at "Bioorganic chemistry"

DOI: 10.1016/j.bioorg.2019.103111

Abstract: Type 2 diabetes mellitus (T2DM) is a disorder distinguished by resisting insulin effects and/or its reduced secretion leading to high blood sugar levels. It is fast becoming epidemic worldwide and is a major cause of… read more here.

Keywords: hplc; teneligliptin; method; dapagliflozin empagliflozin ... See more keywords