The Central Dogma revisited: Insights from protein synthesis, CRISPR, and beyond
Sign Up to like & getrecommendations! Published in 2022 at "Wiley Interdisciplinary Reviews: RNA"
DOI: 10.1002/wrna.1718
Abstract: Francis Crick advanced two distinct but interrelated fundamental principles of molecular biology: (1) the Sequence Hypothesis and (2) the Central Dogma. The Sequence Hypothesis defines biological information transfer as the residue‐by‐residue transfer of sequence information… read more here.
Keywords: information; transfer; dogma; protein synthesis ... See more keywords
An ancestral fold reveals the evolutionary link between RNA polymerase and ribosomal proteins
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-50013-9
Abstract: Numerous molecular machines are required to drive the central dogma of molecular biology. However, the means by which these numerous proteins emerged in the early evolutionary stage of life remains enigmatic. Many of them possess… read more here.
Keywords: barrel folds; ribosomal proteins; biology; fold ... See more keywords
Feedback to the central dogma: cytoplasmic mRNA decay and transcription are interdependent processes
Sign Up to like & getrecommendations! Published in 2019 at "Critical Reviews in Biochemistry and Molecular Biology"
DOI: 10.1080/10409238.2019.1679083
Abstract: Abstract Transcription and RNA decay are key determinants of gene expression; these processes are typically considered as the uncoupled beginning and end of the messenger RNA (mRNA) lifecycle. Here we describe the growing number of… read more here.
Keywords: transcription; decay; central dogma; gene expression ... See more keywords
Multiple-image encryption algorithm based on genetic central dogma
Sign Up to like & getrecommendations! Published in 2022 at "Physica Scripta"
DOI: 10.1088/1402-4896/ac66a1
Abstract: A large number of images are generated and distributed in various fields every day. To protect the image information from being stolen during the network transmission, this paper proposes a multiple-image encryption algorithm based on… read more here.
Keywords: image encryption; central dogma; genetic central; multiple image ... See more keywords
mSphere of Influence: Revisiting the central dogma, again!
Sign Up to like & getrecommendations! Published in 2024 at "mSphere"
DOI: 10.1128/msphere.00398-24
Abstract: ABSTRACT Dr. Parimal Samir works in the field of host–pathogen interactions. In this mSphere of Influence article, he reflects on how the manuscript entitled “De novo gene synthesis by an antiviral reverse transcriptase” by Samuel… read more here.
Keywords: msphere influence; influence revisiting; central dogma; revisiting central ... See more keywords