TAAR1-Dependent and -Independent Actions of Tyramine in Interaction With Glutamate Underlie Central Effects of Monoamine Oxidase Inhibition
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DOI: 10.1016/j.biopsych.2020.12.008
Abstract: BACKGROUND Monoamine oxidase inhibitors (MAOIs) exert therapeutic actions by elevating extracellular levels of monoamines in the brain. Irreversible MAOIs cause serious hypertensive crises owing to peripheral accumulation of tyramine, but the role of tyramine in… read more here.
Keywords: central effects; accumulation; interaction glutamate; monoamine oxidase ... See more keywords
Effects of long-term non-traumatic noise exposure on the adult central auditory system. Hearing problems without hearing loss
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DOI: 10.1016/j.heares.2016.10.015
Abstract: It is known that hearing loss induces plastic changes in the brain, causing loudness recruitment and hyperacusis, increased spontaneous firing rates and neural synchrony, reorganizations of the cortical tonotopic maps, and tinnitus. Much less in… read more here.
Keywords: hearing loss; central effects; auditory; hearing problems ... See more keywords
The Central Effects of Botulinum Toxin in Dystonia and Spasticity
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DOI: 10.3390/toxins13020155
Abstract: In dystonic and spastic movement disorders, however different in their pathophysiological mechanisms, a similar impairment of sensorimotor control with special emphasis on afferentation is assumed. Peripheral intervention on afferent inputs evokes plastic changes within the… read more here.
Keywords: dystonia spasticity; central effects; effects botulinum; toxin dystonia ... See more keywords