All roads lead to IL-6: A central hub of cardiometabolic signaling.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2018.02.062
Abstract: DOI of original article: https://doi.org/10.1016/j.ijcard ⁎ Corresponding author at: Division of Cardiovascu Medicine, Brigham and Women's Hospital, Harvard Me Pasteur, Boston, MA 02115, United States. E-mail address: [email protected] (P. Libby). 1 This author takes responsibility… read more here.
Keywords: central hub; roads lead; hub cardiometabolic; lead central ... See more keywords
mTOR as a central hub of nutrient signalling and cell growth
Sign Up to like & getrecommendations! Published in 2019 at "Nature Cell Biology"
DOI: 10.1038/s41556-018-0205-1
Abstract: The highly conserved protein kinase mechanistic target of rapamycin (mTOR; originally known as mammalian target of rapamycin) is a central cell growth regulator connecting cellular metabolism and growth with a wide range of environmental inputs… read more here.
Keywords: central hub; cell; cell growth; mtor central ... See more keywords
Hexokinase as a Central Hub in Neurodegeneration: From Metabolic Dysfunction to Therapeutic Innovation.
Sign Up to like & getrecommendations! Published in 2025 at "Aging and disease"
DOI: 10.14336/ad.2025.0891
Abstract: Neurodegenerative diseases represent an escalating global health crisis affecting more than 55 million people worldwide; however, underlying mechanisms remain unclear, and therapeutic breakthroughs are elusive. Emerging evidence indicates that hexokinase (HK), the rate-limiting glycolytic enzyme,… read more here.
Keywords: hexokinase central; dysfunction; hub neurodegeneration; neurodegeneration metabolic ... See more keywords
The Nucleolus: A Central Hub for Ribosome Biogenesis and Cellular Regulatory Signals
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms26094174
Abstract: The nucleolus is the most prominent nuclear domain in eukaryotic cells, primarily responsible for ribosome biogenesis. It synthesizes and processes precursor ribosomal RNA (pre-rRNA) into mature rRNAs, assembling the 40S and 60S ribosomal subunits, which… read more here.
Keywords: biogenesis cellular; nucleolus central; ribosome biogenesis; hub ribosome ... See more keywords